Blog
B Cell Types, Antigen Recognition & Activation
What is a B Cell?
Most of our immune system is dependent on the huge diversity of immunoglobulin receptors called antibodies which have the
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24th May 2022
CXCL16 – Review
CXCL16/SR-POX gene has five exons, spans 6283 bp and is found on chromosome 17, position 17p13.2 (Huang et al., 2010) (genecards). CXCL16, also known as SR-PSOX, is a multi-functiona
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24th May 2022
NLRP3 Inflammasome & Cytokine Secretion
Nod-like receptors
Nod like receptors (NLRs) are a versatile family of relatively recently discovered intracellular receptors which have a br
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23rd May 2022
Dendritic Cells - Markers, Activation & Subtypes
What is a Dendritic Cell?
Dendritic cells (DCs) are a type of immune cell that acts as a messenger between the innate and adaptive immune sys
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9th May 2022
Macrophage, M1 & M2, Polarization and Function
What is a Macrophage?
Macrophages are a type of white blood cell of the immune system that engulfs and digests cellular debris, foreign subst
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14th Apr 2022
NK Cells, Markers & Function
What are NK Cells?
Natural Killer (NK) cells were first described in the mid-1970’s as a population of innate lymphocytes that were abl
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13th Apr 2022
C reactive protein
If you've been feeling under the weather, your doctor might have ordered a test to check for c-reactive proteins. But what are c-reactive proteins, and what do they do? In this blog
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25th Mar 2022
Monocytes: An Overview
Monocytes: An overview
Monocytes are a type of white blood cell that play an important role in the immune system. Monocytes are produced in the bone marrow, and they have several funct
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22nd Mar 2022
CD Markers Expression on B Cells
B cells are an important part of the immune system. They play a key role in immunity by producing antibodies that help fight off infection. One way to identify and study B cells is b
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16th Mar 2022
Mouse Monoclonal Antibody
Mouse monoclonal antibodies are a valuable tool in the biomedical field. They can be used for a variety of applications, from research to clinical diagnostics. In this blog post, we
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4th Mar 2022
Immunophenotyping of T Lymphocytes: A Guide
Estimated reading time: 5 minutes
T lymphocytes are type of white blood cell that plays a crucial role in the immune system. There are many different types of T cells, and it is importa
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3rd Mar 2022
CD25 Marker
What is CD25?
CD25, also known as Cluster of Differentiation 25, alpha chain of the high-affinity interleukin-2 receptor (IL2RA) and T11 anti
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15th Feb 2022
CD52 Expression
What is CD52?
Cluster Of Differentiation 52 (CD52) is a highly expressed membrane glycoprotein which is present on the surface of immune cell
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15th Feb 2022
CD31: A Comprehensive Look at an Essential Biomarker
What is CD31?
CD31, also known as PECAM-1, was originally described as a cell surface antigen present on platelets and megakaryocytes. CD31 is
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15th Feb 2022
CD33 Marker
What is CD33?
CD33 is a glycoprotein found on the surface of cells belonging to myeloid lineage. CD33 binds to CD3 in order to help T-cells rec
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21st Jan 2022
What are MHC Class I and II molecules?
What are MHC Class I molecules?
The MHC class I is a glycoprotein that is expressed on all nucleated cells of the human body. MHC class I are
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18th Jan 2022
How do antibodies work?
Antibodies are a special class of Y shaped proteins that help guard your body from invading viruses and bacteria. They do this by either neutralizing the dangerous
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17th Jan 2022
What is an Antigen?
Antigen's are foreign molecules recognised by the immune system.
Antigens can be protein, carbohydrate, lipid or nucleic acid molecules.
Examples include viruses and bacteria as
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15th Jan 2022
chemokine receptors and ligands
Chemokines are highly conserved cytokines that control the movement of cells around the body. All 45 members of the chemokine family can be divided into 4 subfamilies depending on th
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1st Dec 2021
ST2 and IL33
ST2, a member of the IL-1R Subfamily
ST2 is a member of the IL-1R subfamily and was identified in 1989 [1]. The ST2 gene is located on chromoso
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7th Oct 2021
Cortisol and the immune response
By Sinéad Kinsella PhD
What is Cortisol?
Cortisol is a steroid hormone, classified as a member of the glucocorticoid family of hormones which a plethora of physiological process
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6th Oct 2021
Data Science for Immunologists | Assay Genie
By Dr. Niclas Thomas
“Data science” is a recent addition to the vocabulary of analytics, and can mean many different things to different people. As fa
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20th Aug 2021
Immuno-Biomaterial Development | Assay Genie
Background
I am a 3rd year PhD student in Trinity College Dublin and my project is very much an interdisciplinary one. I’m very lucky to get to work between two great labs, Dr. Aisling Dunn
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20th Aug 2021
microbiota & immune system signaling | Assay Genie
You are only part human.
In some ways, you are as much bacteria as you are mammal, and in some ways bacteria make up far more of you than your own familiar cells and genes!
It is becoming
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20th Aug 2021