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10700 results for 'team 1'

    PD-1 Blockade in B-Cell Lymphomas: A Comprehensive Overview(Post)

    Understanding PD-1 Blockade in B-Cell Lymphomas Understanding PD-1 Blockade in B-Cell Lymphomas Introduction The programmed cell death prot ...

    Biological Role of GLP-1(Post)

    Glucagon-like peptide-1 (GLP-1) is a critical hormone in the regulation of glucose metabolism and has garnered significant attention due to its therapeutic potential in managing diabetes ...

    PD-1 & PD-L1 Inhibitors(Post)

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    The PD-1 Pathway and Cancer Immunotherapy(Post)

    The initial identification of PD-1 as a potential target for cancer treatment occurred in the late 1990s and early 2000s through studies exploring the regulation of T-cell responses ...

    Heterogeneity of Type 1 diabetes in children(Post)

    Ahmad Gazali PhD candidate, University of Eastern Finland Type 1 diabetes (T1D) is an autoimmune disease where the pancreatic β cells that produce insulin, a key hormone involve ...

    Beyond Burnout: How T Cell Exhaustion Hijacks Cancer Immunity and What We Can Do About It(Post)

    Imagine a highly trained soldier, elite and effective, sent to the front lines of a relentless war. Day after day, they fight without rest, their supplies dwindle, and the enemy never stops coming. E ...

    Volagidemab: A Breakthrough in GLP-1 Receptor Agonists for Metabolic Disorders(Post)

    Quick Facts About VolagidemabWhat is Volagidemab?Volagidemab is a glucagon-like peptide-1 (GLP-1) receptor antagonist designed to regulate glucose metabolism and energy homeostasis.How ...

    Anti-PD-1: Restoring T Cell Function in Cancer Immunotherapy(Post)

    Cancer immunotherapy has revolutionized the treatment landscape for various malignancies. One of the most promising therapeutic strategies is the use of immune checkpoint inhibitors, par ...

    Unlocking a New Immune Checkpoint: The CD47-Thrombospondin-1 Pathway in Cancer(Post)

    Cancer immunotherapy has revolutionized oncology, offering powerful new ways to treat various malignancies by harnessing the body's own immune system. Central to this success are immune checkpoint in ...

    IL-1 Family Signaling: Unraveling the Molecular Orchestra of Immune Regulation(Post)

    The Interleukin-1 (IL-1) family represents a crucial group of signaling molecules that play a pivotal role in regulating the immune system and inflammatory responses. Comprising 11 members, in ...

    Dual PD-1/PD-L2 Blockade: Expanding the Horizons of Cancer Immunotherapy(Post)

    Introduction to PD-1, PD-L1, and PD-L2 in Cancer ImmunotherapyThe PD-1/PD-L1 immune checkpoint pathway has been instrumental in cancer immunotherapy, with PD-1 (programmed death-1) inhib ...

    Reprogramming Regulatory T Cells: A Breakthrough in Cancer Immunotherapy(Post)

    A New Dawn in Cancer Treatment: Reprogramming the Immune System's Own Soldiers For decades, the fight against cancer has been a relentless battle of attrition, with treatments like chemotherapy and ...

    OKRs for Researchers(Post)

    Objectives & Key Results Objectives & Key Results (OKRs) is a framework for setting and tracking goals. At Assay Genie, we've tailored this approach to sui ...

    Scientific Illustrations by Science Picture Co(Post)

    SciencePicture.Co— Scientific & Medical Illustration About SciencePicture.Co is a science and med ...

    Sweet Deception: How a New Antibody Therapy Unmasks Pancreatic Cancer(Post)

    Sweet Deception: How a New Antibody Therapy Unmasks Pancreatic Cancer Sweet Deception: How a New Antibody Therapy Unmasks Pancreatic Cancer Pancreatic can ...

    3D Respiratory Organoids Cell Viability in a High-throughput 384-well Plate Assay(Post)

    The Assay Genie 3D Organoid Cell Viability Assay (AKES081) provided superior results compared to ThermoScientific PrestoBlue, maintaining over 100% viability at all time points in untre ...

    Breakthrough Discovery: Epstein-Barr Virus Identified as Primary Trigger for Lupus(Post)

    Breakthrough Discovery: Epstein-Barr Virus Identified as Primary Trigger for Lupus A groundbreaking study published in November 2025 has provided the most definitive evidence to date that the common ...

    Turning Tumors Against Themselves: In Vivo Reprogramming of Cancer Cells into Dendritic Sentinels(Post)

    Imagine a future where cancer cells, once masters of disguise, are forced to reveal themselves and even train the body's immune system to fight back. This isn't science fiction; it's the groundbreak ...

    3D Organoid Cell Viability Assay: Performance Assessment in Human Colon Organoids(Post)

    The 3D Organoid Cell Viability Assay (AKES081) demonstrated high sensitivity and low cytotoxicity, making it ideal for long incubation studies (24-48 hours) and high-throughput applicat ...

    Unveiling the Potential of Cy3 Wavelength: Illuminating the Path to Advanced Biomedical Imaging(Post)

    In the realm of biomedical imaging, the quest for precision and clarity drives researchers to explore innovative technologies. One such breakthrough is the Cy3 wavelength, a powerful tool revo ...

    Adhesion molecules in atherosclerosis – ICAM1(Post)

    Adhesion Molecules Direct cell-cell interactions are maintained and regulated by cell adhesion molecules. The expression of adhesion molecule ...

    Preeclampsia & immune cell regulation | Assay Genie(Post)

    What is preeclampsia? According to the World Health Organization (WHO), one in ten pregnant women is affected by hypertensive disorders, and preeclampsia ...

    Automation of MR-proANP and MR-proADM ELISA Kits on Dynex DS2 Instrument(Post)

    The Dynex DS2 platform fully automates the MR-proANP and MR-proADM ELISA assays, streamlining sample processing from loading to detection. Automation ensures consistent assay performanc ...

    Icrucumab: Exploring the Role of Anti-Angiogenic Therapy in Cancer Research(Post)

    Quick Facts About IcrucumabWhat is Icrucumab?Icrucumab is a monoclonal antibody that targets vascular endothelial growth factor receptor-1 (VEGFR-1) to inhibit tumor angiogenesis.How Do ...

    Assay Genie launch SARS-CoV-2 qPCR assay(Post)

    SARS-CoV-2 qPCR assay from Assay Genie Assay Genie have just launched a qPCR assay for the detection of SARS-CoV-2. The SARS-CoV-2 One-Step RT-qPCR Kit for Cor ...

    EGF Family (Post)

    Epidermal Growth Factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor epidermal growth factor receptor (EGFR) which triggers ligand-induced ...

    Fenofibrate Usage for Diabetes Damage(Post)

    Fenofibrate, also known as FEN, is a drug that is used to lower cholesterol levels. It works by blocking the absorption of dietary cholesterol in the small intestine and therefore, re ...

    SOCS proteins: Manipulating the immune response(Post)

    Katherine Edwards, PhD Student, Queen’s University Belfast Cytokines play a vital role in immune responses enabling cross-talk between different cell types ...

    Cell Synchronisation Methods(Post)

    What is Cell Synchronisation? Cell synchronisation is a process by which cells at different stages of the cell cycle in a culture are brought to the same phase. Cell synchronisation is ...

    Targeting Immune Checkpoints as Cancer Therapy(Post)

    The advent of immune checkpoint targeting marks a significant milestone in the oncological field, offering a beacon of hope for patients battling cancer. This innovative approach leverages the bo ...

    Diabetic Nephropathy & Diabetic Mellitus(Post)

    Overview of Diabetes Mellitus Diabetes mellitus (DM) is a major epidemic that affects over 347 million people worldwide (Danaei et al. 2011). The World He ...

    Understanding activating PIK3CA mutations in human disease(Post)

    Ralitsa R. Madsen – University of Cambridge Metabolic Research Laboratories Each one of us is the result of an extraordinary developmental proce ...

    Ladiratuzumab Vedotin: Targeting TNBC with Next-Gen ADC Therapy(Post)

    Quick Facts About Ladiratuzumab VedotinWhat is Ladiratuzumab Vedotin?Ladiratuzumab Vedotin is an antibody-drug conjugate (ADC) designed to target LIV-1, a protein commonly expressed in ...

    ILC2: The Immune Cell That Fights Allergies and Infections(Post)

    ILC2 - Function, Cytokines, and Role in Health and Disease A quick guide to IL2C ...

    LAG-3: Revitalizing T Cells in Exhaustion for Combination Therapies(Post)

    Lymphocyte Activation Gene-3 (LAG-3) is an immune checkpoint receptor that plays a critical role in regulating T cell function. In recent years, LAG-3 has emerged as a potential target f ...

    Pembrolizumab: Unveiling Its Mechanism and Research Applications with Biosimilars(Post)

    Key Facts: PembrolizumabIs Pembrolizumab Safe?Pembrolizumab is widely recognized as safe for most patients, with side effects ranging from mild to severe. Commonly reported side effects ...

    Interferons(Post)

    Interferons (IFNs) are a group of signalling proteins that are produced and released from cells in response to viral infection and other stimuli such as normal and tumour cell survival and ...

    Anti-CTLA-4: Unleashing the Power of T Cells in Combination Immunotherapy(Post)

    Immunotherapy has revolutionized cancer treatment by harnessing the body's immune system to fight malignancies. Among the notable advancements in this field is the development of immune ...

    VEGF: Inflammation and Tumourigenesis(Post)

    What is VEGF? Vascular Endothelial Growth Factors (VEGFs) are a group of homodimeric polypeptides, and are master regulators of vascular development, maintenance and ...

    PVR: Balancing Immune Activation and Suppression in Cancer(Post)

    PVR (Poliovirus receptor), also known as CD155, is a molecule that plays a dual role in regulating the immune response within the tumor microenvironment. While initially discovered as a ...

    Ras signaling pathway(Post)

    A wide variety of cell surface receptors activate Ras GTPase, including the tyrosine receptor linked to the epidermal growth factor receptor (EGFR) (Wells 1999). Upon receptor stimulation, son ...

    ST2 and IL33(Post)

    ST2, a member of the IL-1R Subfamily ST2 is a member of the IL-1R subfamily and was identified in 1989 [1]. The ST2 gene is located on chromos ...

    Passaging Hybridoma Cells: A Detailed Guide(Post)

    Hybridoma cells are essential tools for producing monoclonal antibodies and are derived by fusing B lymphocytes (antibody-producing cells) with myeloma cells (cancer cells) to achieve bo ...

    IQGAP1 signaling review(Post)

    IQGAP1: IQ-motif containing GTPase-activating-like protein-1 reviewIQ motif-containing GTPase-activating-like protein-1 (IQGAP1) is a 190 KDa protein that belongs to a conserved family of s ...

    The Battle of Antibiotics: Penicillin vs. Streptomycin(Post)

    In the realm of medicine, antibiotics are akin to superheroes, combating bacterial infections with unwavering efficacy. Among these, two stalwarts stand out: penicillin and streptomycin. These ...

    Auto-inflammatory diseases and genetics (SAIDs)(Post)

    Shelly Pathak PhD candidate, University of Leeds SAIDs Systemic Auto-inflammatory diseases (SAIDs) have been defined as a group of mainly inherited disorde ...

    Sensing Danger: The Biology of TLR-Mediated Inflammation(Post)

    By Eoin Mac Réamoinn Toll-like receptors (TLRs) are renowned for their fundamental roles in innate sensing and initiating inflammatory responses. TLR ...

    Angiotensin Pathways: Unlocking the Secrets to Blood Pressure Regulation and Beyond(Post)

    The angiotensin pathway is a pivotal hormonal system that plays a crucial role in regulating blood pressure and maintaining fluid and electrolyte balance within the body. This complex biochemical ...

    Validation of MycoGenie Rapid Mycoplasma Detection Kit - A highly sensitive visual determination method for Mycoplasma detection.(Post)

    The MycoGenie Rapid Mycoplasma Detection Kit enables the detection of 28 Mycoplasma species in under 1 hour using a simple visual determination method, eliminating the need for expensiv ...

    LILT: A Novel Immune Checkpoint for Cancer Therapy(Post)

    Recent advances in immunotherapy have highlighted the importance of targeting immune checkpoints to enhance the immune system’s ability to combat cancer. A new potential target in this g ...

    Enhancing PD-L1 Stability Through EZH2 Inhibition(Post)

    Enhancing PD-L1 Stability: The Role of EZH2 InhibitionIn recent years, the role of PD-L1 (Programmed Death-Ligand 1) in cancer immunotherapy has garnered significant attention, particularly regarding ...

    Enhancing Cancer Research: Syngeneic Mouse Models and Immune Checkpoint Inhibitors(Post)

    Enhancing Cancer Research: Syngeneic Mouse Models and Immune Checkpoint Inhibitors A quick guide to Syngeneic Mouse Models Syngeneic Mouse Models Cancer research has seen rem ...

    Targeting Immune Checkpoints as Cancer Therapy(Post)

    In recent years, the field of oncology has witnessed a paradigm shift with the advent of immunotherapy, a treatment modality that harnesses the body's immune system to combat cancer. Among the mo ...

    HMGB1 in inflammation and cancer(Post)

    HMGB1 Functional Overview High mobility group box 1 ( HMGB1), a member of the high-mobility group (HMG) family, was first identified in the thymus in 1973 a ...

    Understanding the mTOR Signaling Pathway: A Key Player in Cell Growth and Metabolism(Post)

    The mammalian target of rapamycin (mTOR) signaling pathway is a crucial regulator of cell growth and metabolism, responding to environmental cues and cellular energy status. This pathway's signif ...

    SARS-CoV-2 테스트 키트 - 원스텝 RT-qPCR 키트(Post)

    SARS-CoV-2 검사 키트-코로나 바이러스 검사를위한 원스텝 RT-qPCR 키트 (2019-nCoV 종) 강력하고 재현 가능한 원스텝 코로나 바이러스 검사 (2019-nCoV종) ...

    CV writing tips for scientists(Post)

    Making the switch! This article provides some help on CV writing tips for scientists for PhDs and PostDocs looking for jobs outside of academia and what they might need to ...

    Sandwich ELISA: Step-by-Step Protocol & Troubleshooting(Post)

    Written by Seán Mac Fhearraigh, PhD  •  Updated: 19 May 2026  •  ~10 min read Quick Answer A sandwich ELISA uses two antib ...

    Tunel 1-Step Assay Kits(Page)

    1-Step TUNEL Kits Unique 1-Step Non-Toxic Dewaxing Step for Late Stage Apoptosis Detection Explore TUNEL Assays ...

    In Vivo Functional Grade Antibodies(Page)

    Functional Grade In Vivo AntibodiesOur low endotoxin mAbs for translational and preclinical animal studies are more efficacious and cost effective than competitors!Explore In Vivo mAbsE ...

    Custom Protein(Page)

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    At Assay Genie, we're proud to support scientists in acheiving their research goals around the globe! Working with the right distributors is an important part of achieving our mission. C ...

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    Assay Genie Mission(Page)

    We started Assay Genie from a small facility in 2017 to solve the biggest problems facing R&D scientists: how to achieve optimal resu ...

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    Custom In Vivo Antibodies(Page)

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    Making Scientists Smile...Empowering researchers with cutting-edge products and exceptional support -because great science starts with a smileThe Science of GrowthInnovation never stand ...

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    Have a question? We’re here to help! You can reach us by filling out the contact form, sending us an email, giving us a call, or chatting live with a member of our team. We ai ...

    Custom Antibody(Page)

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    Animal DIY ELISA Kits(Page)

    Animal DIY ELISA Kits Maximise your research budget! Animal DIY (Do-It-Yourself) ELISA kits are sets of reagents to develop your very own san ...

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    Create your own custom multiplex assay with over 400 analytes to choose from! At Assay Genie we can develop custom assays to meet your research needs within 10 days! To find out more infor ...

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    How do I place an order? Customers may place an order in 3 ways. Orders can be made online via pro-forma invoice, on our website, or via email by emailing ord ...

    Multiplex Assays(Page)

    Multiplex Assays "It’s like doing 24 different ELISA in every well!" GeniePlex Multiplex Assays allow researchers to quantify up to 24 analytes in as little as 15μL of sample ...

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        Chemokines   Key Research Areas       C Chemokine Ligands XCL1/Lymphot ...

    Mouse Multiplex Inflammation ELISA Panels(Page)

    The ELISA Genie, Mouse inflammation multiplex assays utilizes multiple bead populations differentiated by size and different levels of fluorescence intensity. With multiple sizes of bea ...

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    PharmaGenie ELISA Validated According to ISO Quality Systems Highly validated ELISA designed to exceed the needs of biopharma R&D s ...

    Co-Immunoprecipitation (co-IP) Protocol(Page)

    Co-immunoprecipitation Protocol A detailed guide of how Co-IP works, a step by step Co-IP protocol and some hints & tips for your Co-IP workflow! Introductio ...

    Adaptive immune system molecules(Page)

    Co-stimulatory and Co-inhibitory Molecules in Adaptive Immunity The adaptive immune system is in part regulated by a vast array of co-stim ...

    Customer Validated Multiplex Panels(Page)

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    Beta Actin Monoclonal Antibody(Page)

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    Adipocytokines(Page)

    Adipocytokines or adipokines are bioactive molecules that are produced by adipose tissue. They comprise cytokines, chemokines coagulation factors and factors involved ...

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    Non-Human Primate Multiplex ELISA Panels(Page)

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    ELISA Sampler Packs Based on thousands of citations and years of scientific endeavour, Assay Genie has developed ELISA Sampler Packs. An ELISA Sampler Pack is a ...

    RIPA Buffer Recipe(Page)

    What is RIPA Buffer? RIPA (Radio Immuno Precipitation Assay) buffer is primarily used when conducting a western blot or immunoprecipatation assay. A RIPA buffer is used in order to l ...

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    Cell-Based ELISA Kits No More Western Blots! Over 1,600 Cell-Based ELISA kits to measure the relative levels of intracellular and phosphorylat ...

    COVID-19 Swab Test(Page)

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    DNA Assembly Cloning(Page)

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    Apoptosis Assays(Page)

    Assay Genie has developed an extensive suite of assays to measure various forms of cell death. We provide highly sensitive & reprod ...

    Western Blot Protocol & Troubleshooting Guide(Page)

    The Ultimate Western Blot Guide At Assay Ge ...

    Pre-clinical & Large Animal Antibodies(Page)

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