The Protein MAX Polyclonal Antibody (CAB2157) is a valuable tool for researchers studying protein expression and function. This antibody, produced in rabbits, is highly specific for its target protein and has been validated for use in Western blot applications. The Protein MAX Polyclonal Antibody binds to the target protein, allowing for accurate detection and analysis in a variety of cell types. Its high reactivity with human samples makes it ideal for studies in immunology, cell biology, and cancer research.
The target protein, which is not specified in the provided URL, likely plays a crucial role in cellular processes and may be involved in disease pathways. By using the Protein MAX Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of this protein, potentially leading to new discoveries and therapeutic strategies.
Product Name:
MAX Rabbit Polyclonal Antibody
SKU:
CAB2157
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human MAX (NP_002373.3).
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4149
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse kidney, using MAX antibody (CAB2157) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 150s.
