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    Androgenic steroid action in breast cancer(Post)

    By Rachel Bleach, PhD Student, RCSI By the age of 79 years, 1 in 14 women will develop breast cancer (Global Burden of Disease Cancer 2017). Beatson reporte ...

    Antigen Presenting Cells (APCs) and cancer immunotherapy(Post)

    Explore antigen presentation's crucial role in adaptive immunity and its impact on cancer immunotherapy, highlighting the diversity and function of MHC class I molecules. Key Takeawa ...

    MHC Class I vs Class II: Key Differences & Functions [Guide](Post)

    Major Histocompatibility Complex (MHC) molecules are essential for immune recognition and response. They are specialized glycoproteins that present antigens to T cells, allowing the immu ...

    Estrogen and Breast Cancer: a Nuclear (Receptor) War(Post)

    By Dr. Lisa Dwane, Postdoctoral Researcher, Royal College of Surgeons in Ireland The first link between estrogen and breast cancer was made in the ...

    Hijacking the Skull's Gateways: A New 'Backdoor' for Brain Drug Delivery(Post)

    For decades, the brain has been considered an immune sanctuary, protected by the formidable blood-brain barrier. This intricate defense system, while vital for safeguarding our most complex organ, h ...

    Pathological functions of IL-33/ST2 in IBD and Cancer(Post)

    By Charlotte O'Donnell PhD ...

    B Cells: Function, Types, Activation & Role in Immunity(Post)

    B Cell Types, Antigen Recognition & Activation A comprehensive guide to B cells! Introduction B cells, a vital component of the immune system, ...

    Advantages of Small Molecule Inhibitors in Therapeutic Interventions(Post)

    Small molecule inhibitors represent a significant advancement in the field of therapeutic interventions, offering a versatile approach to treating a myriad of diseases, including cancer, viral in ...

    Unraveling the Complexity of the Notch Signaling Pathway: A Key Player in Development and Disease(Post)

    The Notch signaling pathway is a highly conserved cellular communication system that plays a crucial role in various biological processes, including embryonic development, tissue homeostasis, ...

    Phosphatases and PTP1B – Mini review(Post)

    IntroductionThe human kinome is estimated to contain 518 genes, in comparison to the estimated 180 genes that comprise the phosphatome (Arena et al., 2005). These kinase genes represent a signi ...

    PCR Detection of COVID-19 (SARS-CoV-2)(Post)

    PCR Detection of COVID-19 (SARS-CoV-2) Contents Background Assay Information Sample Types   & ...

    Tocilizumab (Actemra®) in COVID-19 Treatment(Post)

    Tocilizumab (Actemra®) in COVID-19 Treatment What is Tocilizumab? Tocilizumab, also called atlizumab, is an immunosuppres ...

    NLRP3 Inflammasome & Cytokine Secretion(Post)

    Nod-like receptors Nod like receptors (NLRs) are a versatile family of relatively recently discovered intracellular receptors which have a b ...

    Build a science blog to progress your career(Post)

    What do scientists consider their skill set when looking for jobs outside of academia? Mine where hard to sum. I was a PhD in cell biology. I could Western Blot, I had used thousands of ant ...

    Hydroxychloroquine: Potential Treatment for COVID-19(Post)

    Hydroxychloroquine: Potential Treatment for COVID-19 What is Hydroxychloroquine? Hydroxychloroquine (HC ...

    CTLA-4 in Breast Cancer: Insights for Immunotherapy(Post)

    The Role of CTLA-4 in Breast Cancer: Implications for ImmunotherapyBreast cancer (BC) remains one of the most prevalent malignancies affecting women worldwide, with significant morbidity and mortalit ...

    COVID-19 (Pflegepunkt) Schnelltest | Assay Genie(Post)

    COVID-19 Schnelltest (Pflegepunkt) Beschreibung                     &nb ...

    Enhancing Cancer Research: Syngeneic Mouse Models and Immune Checkpoint Inhibitors(Post)

    Enhancing Cancer Research: Syngeneic Mouse Models and Immune Checkpoint Inhibitors A quick guide to Syngeneic Mouse Models Syngeneic Mouse Models Cancer research has seen rem ...

    The Powerhouse of Immunity: How Mitochondrial Fitness Fuels the Fight Against Cancer(Post)

    Why do powerful cancer immunotherapies work wonders for some patients but fail for others? The answer may lie not just in the cancer cells themselves, but in the energy levels of our own immune warri ...

    The Role of ACE2 in SARS-CoV-2(Post)

    Structure, Function, and Detection Assays for COVID-2019 Background The global spread of the novel co ...

    How do different types of vaccines work? (Post)

    What is a vaccine? A vaccine is a pharmacological product that gives the recieving patient's immune system a chance to learn how to fight infection with decreased risk of illness. Vacc ...

    CV writing tips for scientists(Post)

    Making the switch! This article provides some help on CV writing tips for scientists for PhDs and PostDocs looking for jobs outside of academia and what they might need to ...

    The Role of Tumor Suppressor Genes in Cancer: Knudson Hypothesis & Oncogenes(Post)

    The focus of this article is Tumor Suppressor Genes. There are various different types of tumor suppressor genes, with BRCA being one of the most popular. The role of Tumor Suppressor Genes in Ca ...

    Tau proteins: An Overview (Post)

    The tau protein is a hot topic in the scientific world right now. This little-known protein has been linked to Alzheimer's disease, Parkinson's disease, and other neurodegenerative dise ...

    Human Papilloma Virus (HPV) Methylation Analysis(Post)

    Stephen Reynolds, PhD Student, CERVIVA and Trinity College Dublin We hear almost daily now how everyone in their lifetime will be touched by cancer either directly or through a close f ...

    Ovarian Cancer: Symptoms, Causes, Diagnosis and Treatment(Post)

    Ovarian cancer is the fourth most common cancer in women. Ovarian cancer is when the normal cells in the ovary change and grow to form a tumour. Because the ovaries are located deep ...

    Immunometabolism – A therapeutic perspective(Post)

    What is Immunometabolism? Immunometabolism is an exponentially growing, multi-disciplinary field of research aiming at deciphering the dynamic cellular and mol ...

    Leukemia Inhibitory Factor: An Overview (Post)

    Leukemia Inhibitory Factor and JAK-STAT Signalling Pathway Leukemia inhibitory factor (LIF) is a cytokine that belongs to the interleukin-6 (IL-6) family of cytokines. Other members of ...

    Treponema pallidum Antibodies: Comprehensive Guide to Diagnostic and Clinical Relevance(Post)

    Treponema pallidum, the causative agent of syphilis, triggers an immune response that produces antibodies detectable by laboratory tests. Diagnosing syphilis often involves detecting the ...

    Belimumab: Unveiling Its Role in Lupus and Beyond(Post)

    Quick Facts About BelimumabWhat is Belimumab?Belimumab is a monoclonal antibody used to treat systemic lupus erythematosus (SLE), an autoimmune disease. It is marketed under the brand n ...

    Spanish Flu: The Deadliest Pandemic in History(Post)

    The Spanish flu pandemic of 1918-1919 was the deadliest in history. It is estimated that up to 100 million people died from the virus, which is more than three times the number who ...

    Polyclonal Vs Monoclonal antibodies: Key features (Post)

    In the field of immunology and biomedical research, antibodies play a crucial role in identifying and targeting foreign substances in the body. However, not all antibodies are the same. In this b ...

    Amatuximab: Exploring Mesothelin-Targeted Therapy for Cancer Research(Post)

    What You Need to Know About AmatuximabIs Amatuximab safe?Amatuximab has shown a manageable safety profile in clinical trials, with most side effects being mild to moderate. Severe adver ...

    How to be a Confident Speaker (Scientific)(Post)

    Like needles in a haystack, interesting speakers that bring charisma and rock n roll to their talks are hard to come by. No matter what the research interests of the audience, these speakers h ...

    Sci-Hub: Your Proxy to Unrestricted Knowledge(Post)

    Introduction to Sci-Hub In the realm of science and academia, one name has been echoing in every corner of the globe, Sci-Hub. Created by Alexandra Elbakyan, a Kazakhstani computer scientis ...

    Polo-like kinase (Plk1) substrates and mitosis(Post)

    Polo-like kinase (Plk1) Polo-like kinase (Plk1), is a serine/threonine kinase that is active during mitosis (Hamanaka et al., 1995). Its name is derived from its orig ...

    Wnt Signalling Pathway in Immunity(Post)

    What is Wnt Signalling? The Wnt signalling pathway is an evolutionarily conserved pathway that plays critical roles in the regulation of determining cell ...

    The common characteristics of cancer | Assay Genie(Post)

    By Shane Houston, PhD Candidate Queen’s University Belfast Cancer is an age old adversary of the human race. This out-of-control growth of abnormal cells has been a shadow over human health ...

    BDNF in inflammation and neuropathologies(Post)

    BDNF Overview Brain-derived neurotrophic factor (BDNF) is a central mediator of neuroplasticity, a term used to describe the ability of neuron ...

    Innate Viral Immunity & RIG-I in COVID-19(Post)

    RIG-I: Antiviral Properties in COVID-19 (SARS-CoV-2) Infection Key Points RIG-I is a cytosolic RNA ...

    Polatuzumab: Redefining Targeted Therapies in B-Cell Lymphoma(Post)

    What You Need to Know About PolatuzumabWhat is Polatuzumab??Polatuzumab vedotin is an antibody-drug conjugate targeting CD79b, a component of the B-cell receptor, used primarily in B-ce ...

    Rapid COVID Antibody Test | Antibody Tests(Post)

    What does the COVID-19 Rapid POC CE-IVD Test detect? The test detects the presence of patient-generated antibodies against spike protein, the virus which causes the disease COVID-19. The te ...

    Networking tips for scientists(Post)

    During my PhD I knew how networking was important, it helped me source reagents off other labs, get the best advice and helped me land a post doc at Cambridge University. Its not ...

    Galectin Therapeutics(Post)

    Idiopathic Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis (IPF) is a chronic, irreversible and ultimately fatal disease characterized by pro ...

    10 Steps to increase lab productivity(Post)

    How to increase lab productivityWhen you look back at some weeks in the lab it seems like you have achieved nothing and your lab productivity can be low. Your cloning hasn’t worked or your mice ...

    miRNAs as therapeutics and biomarkers for pancreatic cancer(Post)

    Pancreatic cancer survival rates Despite recent advances in our understanding of this disease, pancreatic cancer is one of the world’s most lethal maligna ...

    Inhibiting cell division(Post)

    Unregulated cell growthCancer, although heterogeneous by its very nature, can be broadly defined as a set of diseases characterised by unregulated cell growth leading to invasion of surroundin ...

    Early Diagnosis is key: Pick the weed or allow it destroy the garden?(Post)

    By Catríona Dowling, Post-Doc, RCSI I want you to come on a journey with me where we are going to the botanic gardens. You will pick a section of the garden that is yours: yours to treasure ...

    STING Activators As Cancer Therapeutics(Post)

    The STING (Stimulator of Interferon Genes) pathway plays a pivotal role in the innate immune system's response to cancerous cells and DNA viruses. Exploiting this pathway through STING activators ...

    COVID-19 Workplace Testing(Post)

    Workplace Testing for COVID-19 Corporate Testing for COVID-19 The impact of COVID-19 on the econo ...

    How do Neurons work?(Post)

    A neuron is a cell that processes and transmits information through electrical and chemical signals. There are trillions of them in the human brain, which is able to carry out so many comple ...

    29 PhD Thesis Writing Tips(Post)

    Explore 29 essential tips for crafting a compelling and well-structured PhD thesis, blending effective writing practices with time management and academic rigor for a successful dissertation jour ...

    How to improve your relationship with your PI or Professor(Post)

    After probably a round or two of interviews and a PhD in your pocket you would think that proving yourself in your new lab would not be an issue. After all, they did hire you because you were ...

    Prostate Cancer Markers : What to Look for in Your Test Results(Post)

    In this blog post, we will review prostate cancer markers and what you should look for in your results. Prostate antigen marker (PSA) and p63 are the most common markers found in pr ...

    COVID-19 Vaccine Candidates(Post)

    What is COVID-19 COVID-19, the disease caused by the coronavirus named SARS-CoV-2, first identified in Wuhan, China in December 2019 has spr ...

    Mononuclear Phagocytes in Health and Disease(Post)

    Mononuclear phagocytes, essential in immunity and homeostasis, perform diverse roles from phagocytosis to tissue repair, influencing health and disease. Key Takeaways: Mononuclear ...

    T Cell Types, Activation, Polarization & Function(Post)

    T Cell Types, Activation, Polarization & Function A comprehensive guide to T cells! window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); wi ...

    microbiota & immune system signaling | Assay Genie(Post)

    You are only part human. In some ways, you are as much bacteria as you are mammal, and in some ways bacteria make up far more of you than your own familiar cells and genes! It is becoming ...

    Mesenchymal Stem Cells: Navigating the Frontiers of Regenerative Medicine(Post)

    Mesenchymal stem cells (MSCs) have emerged as pivotal players in the realm of regenerative medicine due to their unique properties and versatile potential. Originally discovered in the bone marro ...

    ELISA Sampler Packs(Page)

    ELISA Sampler Packs Based on thousands of citations and years of scientific endeavour, Assay Genie has developed ELISA Sampler Packs. An ELISA Sampler Pack is a ...

    Top 10 Therapeutics(Page)

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    SARS-CoV-2 Host Cell Proteases(Page)

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    Quick Test Strips & Other Reagents(Page)

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    Arrays (Page)

    Antibody Arrays Detect 7-274 proteins in 10 species! Perfect for biomarker discovery and validation studies! Browse by Research Area ...

    ACE2 Assays(Page)

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    High Sensitivity Cytokine ELISA Kits & Multiplex Panels(Page)

    High Sensitivity Cytokine ELISA Cytokine ELISA Kits & Multiplex ...

    COVID-19 Cytokine Storm Multiplex Assays(Page)

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    Urea Assays(Page)

    Urea Assays At Assay Genie we've developed a range of Urea assays for researchers to analyse key steps in the Urea Pathway.

    TCA Cycle Assays(Page)

    TCA/Krebs Cycle Assays At Assay Genie we've developed a range of TCA assays for researchers to analyse key steps in the Krebs/TCA/Citric Acid cycle pathway. Different Products ...

    SARS-CoV-2 ELISA Kits(Page)

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    Rat Multiplex ELISA Panels(Page)

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    How do I place an order? Customers may place an order in 3 ways. Orders can be made online via pro-forma invoice, on our website, or via email by emailing ord ...

    Pre-clinical & Large Animal Antibodies(Page)

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    Oxidative Stress Assays(Page)

    Oxidative Stress Assays Simple & Sensitive Assays to Investigate Oxidative Stress! ...

    Liver & Kidney Biomarker Assays(Page)

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    Anti-Tag Antibodies(Page)

    Anti-Tag Antibodies Highly Specific and Non-reactive Anti-Tag Antibodies Explore Anti-Tag Antibodies window.SHOGUN_IMAGE_ELEMENTS = window ...

    Non-Human Primate Multiplex ELISA Panels(Page)

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    Apoptosis Assays(Page)

    Assay Genie has developed an extensive suite of assays to measure various forms of cell death. We provide highly sensitive & reprod ...

    ChIP Antibodies(Page)

    ChIP Antibodies Highly Validated ChIP Antibodies Organised by Epigenetic Modifications! window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Arra ...

    Disease and Pathways Tools(Page)

    Disease & Pathway ToolsEmpower you Biomedical ResearchDiscover high-quality tools for studying disease pathways, biomarker discovery, and therapeutic development. Ideal for immunolo ...

    Localised Resources(Page)

    Localised ResourcesMultiple languages avaialableAccess research materials in multiple languages, including French, Spanish, Japanese, and more, to support your global research needs.Get ...

    Mouse Multiplex Inflammation ELISA Panels(Page)

    The ELISA Genie, Mouse inflammation multiplex assays utilizes multiple bead populations differentiated by size and different levels of fluorescence intensity. With multiple sizes of bea ...

    Protocols(Page)

    ProtocolsComprehensive protocols & guidesWhether you're working in drug development, diagnostics, or translational research, our curated library supports reliable assay performance ...

    Cation and Inorganic Ion Assays(Page)

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    Tunel 1-Step Assay Kits(Page)

    1-Step TUNEL Kits Unique 1-Step Non-Toxic Dewaxing Step for Late Stage Apoptosis Detection Explore TUNEL Assays ...

    Sistema di Trasporto Virale con MTM – Tampone Faringeo Generico(Page)

    Skip to main content Edit a Web Page To create a web page (such as an "About Us" page or a contact form), start by choosing the type of page you want and then fill in the other details. Page Type Thi ...

    Amino Acid and Protein Assays(Page)

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    High-Fidelity DNA Polymerase(Page)

    What is DNA Polymerase Fidelity? The fidelity of a DNA polymerase is the result of accurate replication of a desired template. The fidelity of DNA polymerase ...

    Glycolysis & Carbohydrates Assay Kits(Page)

    Glycolysis & Carbohydrates Assays At Assay Genie we've developed a range of Glycolysis & Carbohydrates assays for researchers to analyse key indicators in the glycolysis pathwa ...

    Ferroptosis Assays(Page)

    At Assay Genie we've developed a range of Cell Death & Ferroptosis assays for researchers to analyse key steps in the Ferroptosis pathway.

    DNA Ligation(Page)

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    About Us(Page)

    Making Scientists Smile...Empowering researchers with cutting-edge products and exceptional support -because great science starts with a smileThe Science of GrowthInnovation never stand ...

    SARS-CoV-2 Strains(Page)

    COVID-19 COVID-19, the newest coronavirus to gain international attention, is caused by severe acute respiratory syndrome coronavirus 2. The most common abbrev ...

    Multiplex Premixed Panels(Page)

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    Annexin V Assays(Page)

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    Recombinant Proteins for SARS-CoV-2 Research(Page)

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    Lipid Metabolism Assays(Page)

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    Human Multiplex ELISA Panels(Page)

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    Contact Us(Page)

    Have a question? We’re here to help! You can reach us by filling out the contact form, sending us an email, giving us a call, or chatting live with a member of our team. We ai ...

    Human Multiplex Inflammation ELISA Panels(Page)

    The ELISA Genie, Human Inflammation multiplex assays utilizes multiple bead populations differentiated by size and different levels of fluorescence intensity. With multiple sizes of bea ...

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