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10669 results for 'media base protein mbp'

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    Targeted Protein Degradation: The Next Frontier in Oncology Drug Discovery(Post)

    For decades, cancer drug development has focused on blocking proteins—inhibiting enzymes, antagonizing receptors, disrupting signaling pathways. Yet this approach leaves a vast landscape of disease- ...

    CIDE: The New Bioinformatics Engine Unmasking Secreted Proteins for Precision Immunotherapy(Post)

    For decades, the battle against cancer has focused on the cellular 'soldiers' and the genetic 'blueprints' within them. Yet, a vast, invisible world of communication exists between these cells—a sec ...

    Characteristics of scaffold protein(Post)

    Scaffold Proteins Environmental stimuli result in different biological responses including cell growth, proliferation or apoptosis. How cells translate specific stimuli into a specific cell ...

    Tau proteins: An Overview (Post)

    The tau protein is a hot topic in the scientific world right now. This little-known protein has been linked to Alzheimer's disease, Parkinson's disease, and other neurodegenerative dise ...

    C reactive protein(Post)

    Delve into the world of C-reactive protein (CRP), a critical player in the body's response to inflammation, and understand its role in health and disease. Key Takeaways C-reacti ...

    A Guide To Tau Proteins & Tauopathies(Post)

    Explore the essential role of Tau proteins in neuronal health and their impact in neurodegenerative diseases, unfolding the complexity behind their functions and dysfunctions. Key Takeaways: ...

    Choosing a Fluorescent Protein: A Comprehensive Guide (Post)

    Fluorescent proteins (FPs) have revolutionized the field of molecular and cellular biology, allowing scientists to visualize and track biological processes in live cells with unprecedented clarit ...

    Boiling Proteins for Western Blotting: Optimal Conditions and Best Practices(Post)

    Boiling proteins is a critical step in preparing samples for Western blotting, a technique widely used to detect specific proteins in complex mixtures. Proper heating denatures the prote ...

    SOCS proteins: Manipulating the immune response(Post)

    Katherine Edwards, PhD Student, Queen’s University Belfast Cytokines play a vital role in immune responses enabling cross-talk between different cell types ...

    Protein Kinases: Overview, Classification and Therapeutic Potential(Post)

    Kinases, key enzymes in cellular signaling, phosphorylate proteins to regulate crucial processes, and their modulation has significant implications in disease treatment. Key Takeaways: K ...

    Phosphorothioate: Enhancing Stability in Oligonucleotide-Based Therapies(Post)

    Phosphorothioate is a chemical modification commonly used in oligonucleotide-based therapies to enhance the stability and efficacy of therapeutic nucleic acids. In this modification, one ...

    p53 Protein: Mutations, Cancer Signalling & Tumour Suppression(Post)

    p53, encoded by the TP53 gene on chromosome 17, is a fundamental protein safeguarding against tumor formation. It orchestrates cellular responses to DNA damage and stress, crucially managing cell ...

    GPCRs (G Protein Coupled Receptors): A Guide(Post)

    What Are GPCRs? GPCRs, or G protein-coupled receptors, are a large family of membrane proteins that play a crucial role in cell signaling. They are involved in tran ...

    Bone Morphogenetic Proteins (BMP) – Review(Post)

    Bone Morphogenetic Proteins (BMP) were first discovered in the 1960s by Dr.Marshall Urist, an orthopaedic surgeon at UCLA (Urist 1965). BMPs are classically associated with their roles in limb ...

    Labeling Non-Antibody Proteins and Small Molecules: An Advanced Guide(Post)

    In the evolving landscape of biochemical research and diagnostic assay development, the ability to label non-antibody proteins and small molecules with high precision has become indispensable. Th ...

    Platelet Adhesion Proteins and Ligands: Key Players in Hemostasis and Thrombosis(Post)

    Platelet adhesion is a critical process in the maintenance of hemostasis, the body's response to bleeding. This intricate process involves a series of interactions between platelets, the cellular ...

    Biosimilar: Expanding Access to Monoclonal Antibody-Based Therapies(Post)

    1. What is a Biosimilar? A biosimilar is a biologic medical product that is highly similar to an already-approved reference biologic. While minor differences in clinically inactive ...

    Platinum based cancer drugs and next generation therapeutics(Post)

    Platinum based cancer drugs Despite nearly 50% of all anti-cancer treatments being platinum-based, there is an urgent need to develop novel therapeutics ...

    A Quick Guide to Myelin(Post)

    The myelin sheath is an insulating layer around nerve cells. It is made up of a substance called myelin, which is produced by special cells called oligodendrocytes. Myelin protects the nerve cell ...

    Enhancing PD-L1 Stability Through EZH2 Inhibition(Post)

    Enhancing PD-L1 Stability: The Role of EZH2 InhibitionIn recent years, the role of PD-L1 (Programmed Death-Ligand 1) in cancer immunotherapy has garnered significant attention, particularly regarding ...

    Schwann Cells: Specialized Cells that Support Nerve Function(Post)

    Schwann cells are cells that play a vital role in nerve function. They are responsible for myelinating axons and helping to ensure the transmission of electrical signals between neurons. Schwann ...

    An Overview of the glycoprotein GM-CSF(Post)

    This article breaks down the glycoprotein Granulocyte-macrophage colony-stimulating factor (GM-CSF) detailing its structure, function and therapeutic uses. It also describes its role in im ...

    A Quick Guide To Mycoprotein(Post)

    Mycoprotein is an alternative source of protein that can be used in place of meat. It is made from a fungi called Fusarium venenatum, and is consumed by vegetarians and vegans as a meat su ...

    Oligodendrocytes: Complete Guide + Functions & Development(Post)

    Oligodendrocytes are pivotal CNS cells, integral for myelin formation and nerve function, with implications in various neurological disorders. Key Takeaways Oligodendrocytes are speci ...

    Types of Glial Cells(Post)

    Microglia Astrocytes Oligodendrocytes Glial ...

    Narsoplimab: Targeting MASP-2 to Advance Therapies in Immune-Mediated Disorders(Post)

    Quick Facts About NarsoplimabWhat is Narsoplimab?Narsoplimab is a human monoclonal antibody that targets MASP-2, a key enzyme in the lectin pathway of the complement system.What is the ...

    Neural Stem Cell Differentiation: Pathways and Lineage-Specific Markers(Post)

    Understanding the differentiation pathways of neural stem cells (NSCs) and the identification of lineage-specific markers is a cornerstone in the field of neurobiology and regenerative medicine.

    What Are Oligodendrocytes? Functions, Markers & Disease Links(Post)

    What Are Oligodendrocytes? Functions, Markers & Disease LinksOligodendrocytes are pivotal CNS cells, integral for myelin formation and nerve function, with implications in various n ...

    RIPA Buffer Recipe - Cell Lysis | Assay Genie(Post)

    RIPA (Radio Immuno Precipitation Assay) buffer is mostly used when carrying out a western blot or immunoprecipatation assay. A RIPA buffer is used in order to lyse cells and extract protein fr ...

    Sensing Danger: The Biology of TLR-Mediated Inflammation(Post)

    By Eoin Mac Réamoinn Toll-like receptors (TLRs) are renowned for their fundamental roles in innate sensing and initiating inflammatory responses. TLR ...

    Granulocytes Guide(Post)

    Explore the diverse roles and functionalities of granulocytes - neutrophils, eosinophils, basophils, and mast cells - as they form a critical line of defense in the immune system, res ...

    Validation of MycoGenie Rapid Mycoplasma Detection Kit - A highly sensitive visual determination method for Mycoplasma detection.(Post)

    The MycoGenie Rapid Mycoplasma Detection Kit enables the detection of 28 Mycoplasma species in under 1 hour using a simple visual determination method, eliminating the need for expensiv ...

    COVID-19 Vaccine Candidates(Post)

    What is COVID-19 COVID-19, the disease caused by the coronavirus named SARS-CoV-2, first identified in Wuhan, China in December 2019 has spr ...

    ELISA vs Western Blot: Which Technique Should You Choose?(Post)

    Written by Seán Mac Fhearraigh, PhD  •  Updated: 19 May 2026  •  ~9 min read Quick Answer ELISA and Western Blot are both antibody-based protein detection methods. ELISA is f ...

    Western Blot Training: A Comprehensive Guide(Post)

    Western blotting, a cornerstone technique in molecular biology, biochemistry, and immunogenetics, is pivotal for detecting specific proteins in a sample. Its applications span various scientific ...

    Mycoplasma in Cell Culture Detection Guide(Post)

    As a PhD student delving deep into the realm of cellular biology, there is one antagonist that consistently challenges my research: mycoplasma. This microscopic bacterium, with its ...

    How do different types of vaccines work? (Post)

    What is a vaccine? A vaccine is a pharmacological product that gives the recieving patient's immune system a chance to learn how to fight infection with decreased risk of illness. Vacc ...

    Amino Acids: Types, Functions, Structure & Essential Guide(Post)

    Amino acids are the fundamental units of proteins, playing critical roles in virtually every biological process. Composed of a central carbon atom bonded to an amino group (-NH₂), a carb ...

    Agarose vs Polyacrylamide: A Comparative Analysis(Post)

    In the realm of molecular biology and biochemistry, gel electrophoresis stands as a cornerstone technique for the separation and analysis of macromolecules such as DNA, RNA, and proteins. Central ...

    Fluorescence Resonance Energy Transfer (FRET) Assays: An Insight into Molecular Interactions(Post)

    Fluorescence Resonance Energy Transfer (FRET) assays represent a pivotal technique in the molecular and cellular biology fields, enabling the examination of protein interactions, nucleic acid str ...

    Protease vs Peptidase: Understanding Enzymatic Digestion(Post)

    In the complex world of biochemical processes, enzymes play a crucial role in catalyzing various reactions necessary for life. Among these enzymes, proteases and peptidases are fundamental pla ...

    How Furin and ACE2 Interact with the Spike on SARS-CoV-2(Post)

    What is the Coronavirus Spike Protein? COVID-19, the newest coronavirus to gain international attention, is caused by severe acute respirato ...

    Lactobacilli - Structure, Metabolism, and Testing(Post)

    Delving into the world of Lactobacilli, this piece explores their structural intricacies, metabolic functions, and the pivotal role they play in human health. These bacteria, key components in ...

    Novel Gene Therapy for Cystic Fibrosis (Post)

    Novel Gene Therapies for Cystic Fibrosis Cystic Fibrosis Cystic fibrosis (CF) is an autosomal recessive, life-limiting disease resulting from gene mutations that encode the cystic fib ...

    The Role of ACE2 in SARS-CoV-2(Post)

    Structure, Function, and Detection Assays for COVID-2019 Background The global spread of the novel co ...

    JAK-STAT Signalling and Cytokines: The What, How, and Why(Post)

    In the intricate landscape of cellular communication, lies a sophisticated ...

    RNA Extraction for COVID-19 Testing(Post)

    Testing for COVID-19 Since the start of the COVID-19 pandemic, the World Health Organisation have emphasised the crucial impor ...

    Transfection: A Comprehensive Guide (Post)

    Transfection protocols play a crucial role in the realm of molecular biology and genetic research, enabling the introduction of foreign nucleic acids into living cells. This innovat ...

    Blood Coagulation Signaling Pathways: A Critical Overview(Post)

    Blood coagulation is a fundamental physiological process that prevents excessive bleeding when the vascular system is injured. It involves a complex cascade of events that lead to the formation o ...

    Plasma Membrane Markers(Post)

    What is a Plasma Membrane? The plasma membrane, also known as the cell membrane, is a vital component of all cells. It is a thin, semi-permeable barrier that separat ...

    3D Cell Culture: Assay Guide(Post)

    References Key Points Three-dimensional (3D) cell cultures are artificially-created environments in which cells are permitted to grow or interact with their surroundings in a 3D f ...

    LATS1/2 Kinases Review(Post)

    LATS kinases belong to a family of proteins that, in mammals, are comprised of two isoforms, LATS1 and LATS2. Originally identified in Drosophila melanogaster as Warts kinase, LATS1 and LATS2 s ...

    Guide to Western Blot Sample Preparation(Post)

    Western blotting remains a pivotal technique in the molecular biosciences for the detection, quantification, and analysis of proteins. Its utility spans numerous fields, including immunology, de ...

    HERV-K group of endogenous retroviruses and cancer(Post)

    In 2006, upon completion of the Human Genome Project, it was discovered that nearly 8% of the human genome is made up of viral DNA. These viral remnants are composed of ancient germ ...

    Leukemia Inhibitory Factor (LIF)(Post)

    Leukemia Inhibitory Factor (LIF) is a cytokine that plays a crucial role in various physiological processes within the human body. It has gained significant attention in the field o ...

    Unveiling the Potential of Cy3 Wavelength: Illuminating the Path to Advanced Biomedical Imaging(Post)

    In the realm of biomedical imaging, the quest for precision and clarity drives researchers to explore innovative technologies. One such breakthrough is the Cy3 wavelength, a powerful tool revo ...

    Toll-like Receptors: Gatekeepers of Immune Recognition and Response(Post)

    What are Toll Like Receptors? Toll-like receptors (TLRs) are a class of proteins that play a crucial role in the immune system's defense against microbial invaders ...

    Navigating the Intricacies of Intracellular Flow Cytometry: Key Considerations(Post)

    In the evolving landscape of cellular biology, intracellular flow cytometry (ICFC) stands out as a powerful technique for analyzing the complexities within cells. This advanced method extends the ...

    Cell Signalling – Mini Review(Post)

    Cell Signalling Cell signalling pathways have an important role in integrating a plethora of extracellular and intracellular signals to produce a controlled optimal ...

    The Blood Brain Barrier: An Overview (Post)

    What is the blood-brain barrier? The Blood-brain barrier (BBB) is a system of vessels that acts as a structural and chemical barrier between the brain and the rest of the body's circul ...

    Apoptosis Unveiled: Your Complete Guide to Intrinsic & Extrinsic Pathways(Post)

    Apoptosis Unveiled: Your Complete Guide to Intrinsic & Extrinsic PathwaysAt Assay Genie we have created a comprehensive guide outlining everything you need to know about apoptosis!K ...

    Cell Death Pathways: Intrinsic vs Extrinsic Apoptosis Guide(Post)

    At Assay Genie we have created a comprehensive guide outlining everything you need to know about apoptosis! Key Takeaways: Apoptosis is a programmed cell death process, vital for tissu ...

    Interleukin 12 (IL-12) in COVID-19 Vaccines(Post)

    Interleukin 12 in COVID-19 Prophylactics Interleukin 12 is a cytokine with wide-reaching effects in the innate and adaptive immune system. O ...

    Carbon Dioxide sensing in Immune Cells(Post)

    BRIEF HISTORY OF THE “GREEN” EVOLUTION OF OXYGEN AND CARBON DIOXIDE WITHIN OUR ATMOSPHERE Million years ago carbon dioxide (CO2) levels used to be consid ...

    Ubiquitin and Its Role in Cellular Regulation: A Comprehensive Overview of Modifiers and Pathways(Post)

    Ubiquitin is a small, highly conserved protein found in eukaryotic cells that plays a crucial role in regulating various cellular processes. The process of ubiquitination involves the covalent at ...

    Exploring Organelle Markers: Illuminating the Cellular Landscape(Post)

    The eukaryotic cell is a complex and dynamic system with distinct membrane-bound compartments known as organelles, each performing specialized functions essential for cellular survival. To better ...

    Investigating orthohantavirus infections with proteomics(Post)

    Sarah Brun Bar-Yaacov PhD Candidate, University of Liverpool Orthohantaviruses are a group of segmented negative-sense RNA viruses maintained as asympt ...

    What are MHC Class I and II molecules?(Post)

    What are MHC Class I molecules? The MHC class I is a glycoprotein that is expressed on all nucleated cells of the human body. MHC class I are important in disease defense against viruses, b ...

    Fibroblast Markers(Post)

    Fibroblasts, essential components of connective tissues, play vital roles in maintaining tissue structure and function. Their remarkable ability to produce and organize the extracellular matrix ...

    Autophagy alterations in Alzheimer’s disease(Post)

    By Diana-Madalina Stan, PhD student, University of Salford Disease Description Alzheimer’s disease (AD), the most common cause of dementia, is ...

    Streptococcus pneumoniae: Pathogenesis, Diagnosis, and Treatment(Post)

    Streptococcus pneumoniae, commonly known as pneumococcus, is a Gram-positive, encapsulated bacterium that is a leading cause of respiratory and invasive diseases worldwide. It is part of ...

    CRISPR-Cas Screening for Cell Viability(Post)

    Key Points Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a method of gene editing that uses ...

    Insulin Signaling and RTK: An Overview(Post)

    Explore the intricate world of Insulin Signaling and Receptor Tyrosine Kinases (RTKs), pivotal in regulating metabolism and influencing diseases like cancer and atherosclerosis. Key Take ...

    Types of ELISA: Direct, Indirect, Sandwich & Competitive Compared(Post)

    Written by Seán Mac Fhearraigh, PhD  •  Updated: 19 May 2026  •  ~9 min read Quick Answer The five main types of ELISA are sandwich, competitive, direct, indirect and multiple ...

    Proteins(Page)

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    Amino Acid and Protein Assays(Page)

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    Recombinant Proteins for SARS-CoV-2 Research(Page)

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    Cell-Based ELISA Kits (Page)

    Cell-Based ELISA Kits No More Western Blots! Over 1,600 Cell-Based ELISA kits to measure the relative levels of intracellular and phosphorylat ...

    Custom Protein(Page)

    document.addEventListener("DOMContentLoaded",(function(){var e=document.querySelector(".page-sidebar");e&&e.remove(),document.querySelectorAll(".page-heading").forEach((function(e){e.re ...

    RIPA Buffer Recipe(Page)

    What is RIPA Buffer? RIPA (Radio Immuno Precipitation Assay) buffer is primarily used when conducting a western blot or immunoprecipatation assay. A RIPA buffer is used in order to l ...

    Services(Page)

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    Co-Immunoprecipitation (co-IP) Protocol(Page)

    Co-immunoprecipitation Protocol A detailed guide of how Co-IP works, a step by step Co-IP protocol and some hints & tips for your Co-IP workflow! Introductio ...

    COVID-19 Throat Swab Test(Page)

    COVID-19 Throat Swab Test Throat/Oropharyngeal Swabs for Viral Sample Collection The development of diagnostic tests for COVID- ...

    Lipid Metabolism Assays(Page)

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    SARS-CoV-2 ELISA Kits(Page)

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    COVID-19 Assays(Page)

    COVID-19 RAPID Point of Care (POC) tests At Assay Genie we provide a range of COVID-19 rapid tests from a range of suppliers including Acro Biotech, Cellex, G ...

    Western Blot Protocol & Troubleshooting Guide(Page)

    The Ultimate Western Blot Guide At Assay Ge ...

    Subcellular Fractionation Protocol - Mitochrondria, Nuclear, Cytosolic(Page)

    What is Subcellular Fractionation? Subcellular fractionation is the process of iIsolating nuclear, cytosolic and mitochondrial fractions of high purity from tissues. Subcellular fracti ...

    Anti-Tag Antibodies(Page)

    Anti-Tag Antibodies Highly Specific and Non-reactive Anti-Tag Antibodies Explore Anti-Tag Antibodies window.SHOGUN_IMAGE_ELEMENTS = window ...

    Clinical Chemistry Assays(Page)

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    ACE2 Assays(Page)

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    Brochures and Flyers(Page)

    Brochures & FlyersFind the information you needExplore Assay Genie's collection of scientific brochures and product flyers featuring our ELISA kits, antibodies, proteins, and custom ...

    SARS-CoV-2 Strains(Page)

    COVID-19 COVID-19, the newest coronavirus to gain international attention, is caused by severe acute respiratory syndrome coronavirus 2. The most common abbrev ...

    ELISA Kits(Page)

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    Loading Control Antibodies(Page)

    Loading Control Antibodies High Performing Loading Control Antibodies Explore Loading Control Antibodies window.SHOGUN_IMAGE_ELEMENTS = w ...

    Immunohistochemical Staining, Antibodies & Buffers(Page)

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    COVID-19 Rapid Test(Page)

    COVID-19 Rapid Tests What is COVID-19? SARS-CoV-2 is the causative viral agent of the disease COVID-19. It is primarily transmitt ...

    SARS-CoV-2 Host Cell Proteases(Page)

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    Assay Genie Mission(Page)

    We started Assay Genie from a small facility in 2017 to solve the biggest problems facing R&D scientists: how to achieve optimal resu ...

    Site Directed Mutagenesis(Page)

    Key Takeaways: Site-directed mutagenesis (SDM) enables precise DNA sequence alterations. Used for investigating protein activity changes and introducing beneficial mutations. GenieClone ki ...

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