The CBLN2 Monoclonal Antibody (PAC02257) is a valuable tool for researchers studying CBLN2, a protein known for its role in synaptic organization and function in the brain. This antibody, generated in mice, is highly specific to human samples and has been validated for use in immunohistochemistry and Western blotting applications. It binds specifically to the CBLN2 protein, allowing for precise detection and analysis in various experimental setups.CBLN2 is a member of the C1q/tumor necrosis factor superfamily and is involved in synapse formation and maintenance, particularly in the cerebellum. Its function in regulating synaptic transmission and plasticity makes it a key player in understanding neurological disorders and cognitive function.
Research on CBLN2 has potential implications for conditions such as autism spectrum disorders and neurodegenerative diseases, highlighting its importance as a target for further investigation.By utilizing the CBLN2 Monoclonal Antibody, researchers can gain valuable insights into the mechanisms underlying synaptic connectivity and function in the brain, opening up new avenues for therapeutic interventions and treatments for neurological disorders. This antibody is a valuable tool for any study focusing on CBLN2 and its role in synaptic physiology and brain function.
Antibody Name:
CBLN2 Antibody (PACO22257)
Antibody SKU:
PACO22257
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from internal of human CBLN2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from COS cells, using CBLN2 antibody.
Background:
May play role in synaptogenesis induction By similarity.
Synonyms:
cerebellin-2; UNQ1892/PRO4338;
UniProt Protein Function:
CBLN2: May interact with CBLN1, CBLN3 and CBLN4.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 18q22.3Cellular Component: extracellular spaceBiological Process: positive regulation of synaptogenesis
