The CD71 Transferrin Receptor Polyclonal Antibody is a crucial tool for researchers studying the CD71 protein, also known as the transferrin receptor. This antibody is produced using high-quality rabbit hosts and has shown high reactivity with human samples. Validated for use in Western blot applications, it specifically binds to the CD71 protein, allowing for accurate detection and analysis in a variety of cell types.The CD71 protein plays a vital role in cellular iron uptake by binding to transferrin and facilitating the internalization of iron into cells. Its involvement in iron metabolism makes it a key player in various physiological and pathological processes, including cell growth, differentiation, and proliferation.
Research into the CD71 protein is essential for understanding how iron homeostasis is regulated in both normal and disease states.This CD71 Transferrin Receptor Polyclonal Antibody is an invaluable tool for scientists studying iron metabolism, cell biology, and diseases related to iron dysregulation such as anemia, cancer, and neurodegenerative disorders. By targeting the CD71 protein, researchers can gain insights that may lead to the development of new therapeutic approaches for a range of conditions.
Product Name:
CD71/Transferrin Receptor Polyclonal Antibody
SKU:
CAB21622
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-250 of human CD71/Transferrin Receptor (NP_003225.2).
Cell membrane, Melanosome, Secreted, Single-pass type II membrane protein.
Calculated MW:
85kDa
Observed MW:
90kDa
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified.
Purification Method:
Affinity purification
Gene ID:
7037
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using CD71/Transferrin Receptor Rabbit pAb (CAB21622) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
