Description
RNF133 Antibody (PACO11866)
The RNF133 Polyclonal Antibody (PAC011866) is a valuable tool for researchers studying RNF133, a protein involved in cellular processes such as ubiquitination and protein degradation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the RNF133 protein, this antibody enables precise detection and analysis in various cell types, making it an essential tool for studies in cell biology and molecular biology.RNF133 is a key player in the regulation of protein turnover and cellular signaling pathways.
Its involvement in ubiquitination processes suggests a critical role in maintaining cellular homeostasis and responding to environmental stressors. Research on RNF133 could provide valuable insights into mechanisms underlying diseases such as cancer, neurodegenerative disorders, and metabolic dysfunction. By elucidating the functions of RNF133, scientists may uncover new therapeutic targets for treating these conditions.
| Antibody Name: | RNF133 Antibody (PACO11866) |
| Antibody SKU: | PACO11866 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human RNF133 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | ring finger protein 133;RNF133;MGC27072 ; |
| UniProt Protein Function: | RNF133: Has E3 ubiquitin-protein ligase activity. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Ubiquitin conjugating system; EC 6.3.2.-; EC 6.3.2.19; Endoplasmic reticulum; Ubiquitin ligase; Ligase Chromosomal Location of Human Ortholog: 7q31.32 |
| NCBI Summary: | The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene has no intron. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8WVZ7 |
| NCBI GenInfo Identifier: | 74730905 |
| NCBI Gene ID: | 168433 |
| NCBI Accession: | Q8WVZ7.1 |
| UniProt Secondary Accession: | Q8WVZ7,Q8N7G7, A4D0W2, |
| UniProt Related Accession: | Q8WVZ7 |
| Molecular Weight: | 42,294 Da |
| NCBI Full Name: | E3 ubiquitin-protein ligase RNF133 |
| NCBI Synonym Full Names: | ring finger protein 133 |
| NCBI Official Symbol: | RNF133Â Â |
| NCBI Protein Information: | E3 ubiquitin-protein ligase RNF133 |
| UniProt Protein Name: | E3 ubiquitin-protein ligase RNF133 |
| UniProt Synonym Protein Names: | RING finger protein 133 |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | RNF133Â Â |
| UniProt Entry Name: | RN133_HUMAN |
