The SCMH1 Polyclonal Antibody (PAC039322) is a valuable tool for researchers studying the SCMH1 protein, which is involved in chromatin structure maintenance and gene expression regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications.SCMH1, also known as Subunit of the Polycomb Repressor Complex 1 (PRC1), is a key player in epigenetic regulation, specifically involved in the silencing of gene expression through chromatin modification. Dysregulation of SCMH1 has been linked to various diseases, including cancer and developmental disorders, highlighting its importance in research.
By utilizing the SCMH1 Polyclonal Antibody, researchers can detect and analyze the expression of SCMH1 in different cell types, providing insights into its function and potential therapeutic applications in the field of epigenetics and oncology. Understanding the role of SCMH1 in chromatin dynamics and gene regulation is crucial for advancing our knowledge of disease mechanisms and developing targeted interventions.
Antibody Name:
SCMH1 Antibody (PACO39322)
Antibody SKU:
PACO39322
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Polycomb protein SCMH1 protein (201-500AA)
Associates with Polycomb group (PcG) multiprotein complexes; the complex class is required to maintain the transcriptionally repressive state of some genes.
Synonyms:
Polycomb protein SCMH1 (Sex comb on midleg homolog 1), SCMH1
UniProt Protein Function:
SCMH1: Associates with Polycomb group (PcG) multiprotein complexes; the complex class is required to maintain the transcriptionally repressive state of some genes. Belongs to the SCM family. 6 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 1p34Cellular Component: nucleoplasm; nucleus; chromocenterMolecular Function: DNA binding; transcription factor activityBiological Process: anterior/posterior pattern formation; chromatin remodeling; anatomical structure morphogenesis; transcription, DNA-dependent; spermatogenesis; gene silencing; negative regulation of transcription, DNA-dependent
