The THAP6 Polyclonal Antibody (PAC017232) is a valuable tool for researchers studying THAP6, a transcription factor that plays a role in various cellular processes. This antibody, generated in rabbits, is highly specific for human proteins and has been validated for use in Western blot applications. By binding to the THAP6 protein, this antibody allows for the detection and analysis of THAP6 in different cell types, making it ideal for studies in molecular biology and gene regulation.THAP6 is involved in gene expression regulation and has been implicated in processes such as cell proliferation, differentiation, and apoptosis.
Its diverse functions make it a promising target for research into various diseases, including cancer and neurological disorders. Understanding the role of THAP6 can provide insights into disease mechanisms and potentially lead to the development of targeted therapies.Order the THAP6 Polyclonal Antibody (PAC017232) today to advance your research in gene regulation and cellular processes. This highly specific antibody will enable you to explore the functions of THAP6 in different biological contexts, ultimately contributing to a better understanding of its role in health and disease.
Antibody Name:
THAP6 Antibody (PACO17232)
Antibody SKU:
PACO17232
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Full length fusion protein
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17232(THAP6 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
Background:
THAP6 (THAP domain-containing protein 6) is a 222 amino acid, protein that contains one THAP-type zinc finger and exists as two alternatively spliced isoforms. The gene that encodes THAP6 consists of approximately 36,528 bases and maps to human chromosome 4q21.1. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is encoded by a gene that maps to chromosome 4. FGFR-3 is also encoded by a gene located on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acid, mia and polycystic kidney disease.
Synonyms:
THAP domain containing 6
UniProt Protein Function:
THAP6: 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 4q21.1Cellular Component: microtubule cytoskeletonMolecular Function: DNA binding; metal ion binding
