The Tuba1c Polyclonal Antibody (PAC017335) is a valuable tool for researchers studying Tuba1c, a protein involved in cytoskeleton organization and cell motility processes. This antibody, produced using rabbits, exhibits high specificity and sensitivity to human samples, making it suitable for Western blot applications.Tuba1c is a member of the tubulin family, playing a crucial role in microtubule dynamics and cellular structure. Its function in cell proliferation, migration, and differentiation makes it a promising target for research in cell biology, cancer metastasis, and neuronal development.
By detecting Tuba1c expression in various cell types, this antibody facilitates the analysis of its role in different physiological and pathological processes.Understanding the function of Tuba1c is essential for unraveling its contribution to cell behavior and disease progression. This antibody provides a reliable tool for investigating the involvement of Tuba1c in cellular processes, offering insights into potential therapeutic strategies targeting Tuba1c-associated pathways.
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17335(TUBA1C Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela, K562 and NIH/3T3 cell, Primary antibody: PACO17335(TUBA1C Antibody) at dilution 1/400 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO17335(TUBA1C Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
Background:
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the β chain and one at a non-exchangeable site on the α chain.
Synonyms:
tubulin, α 1c
UniProt Protein Function:
TUBA1C: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. Belongs to the tubulin family.Protein type: Cytoskeletal; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 12q13.12Cellular Component: microtubule; nucleus; vesicleMolecular Function: protein binding; structural molecule activityBiological Process: cell division; cytoskeleton-dependent intracellular transport; microtubule-based process
