The XKRX Polyclonal Antibody (PACO20942) is a valuable tool for researchers studying the XKRX protein, an important regulator of cell function. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting. By specifically binding to the XKRX protein, researchers can accurately detect and analyze its expression in different cell types, making it ideal for investigations in the fields of cell biology and cancer research.
The XKRX protein is known to play a crucial role in cellular processes, such as cell growth, proliferation, and apoptosis. Its involvement in these fundamental aspects of cell biology highlights its significance as a potential therapeutic target for diseases like cancer and other proliferative disorders. By delving into the functions of XKRX, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially develop new treatment strategies targeting this protein.
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20942(XKRX Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane 1-3: Human thyroid cancer and liver cancer tissue, human fetal intestines tissue, Primary antibody: PACO20942(XKRX Antibody) at dilution 1/500 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20942(XKRX Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a protein that is related to a component of the XK/Kell complex of the Kell blood group system. The encoded protein includes several transmembrane domains, is known to be exposed to the cell surface, and may function as a membrane transporter.
Synonyms:
XK, Kell blood group complex subunit-related, X-linked
UniProt Protein Function:
XKRX: a protein that is related to a component of the XK/Kell complex of the Kell blood group system. The encoded protein includes several transmembrane domains, is known to be exposed to the cell surface, and may function as a membrane transporter. [provided by RefSeq, May 2010]Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: Xq22.1
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that is related to a component of the XK/Kell complex of the Kell blood group system. The encoded protein includes several transmembrane domains, is known to be exposed to the cell surface, and may function as a membrane transporter. [provided by RefSeq, May 2010]