The ZC3H7B Polyclonal Antibody (PAC021976) is a valuable tool for researchers studying the ZC3H7B protein, a zinc finger protein involved in RNA processing and gene regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ZC3H7B protein, this antibody enables the detection and analysis of ZC3H7B in various cell types, making it an ideal choice for studies in molecular biology and genomics.
ZC3H7B is known to play a crucial role in post-transcriptional regulation, including mRNA stability and translation control. Its involvement in various cellular processes makes it a promising target for research on RNA metabolism, gene expression, and developmental biology. Understanding the function of ZC3H7B can provide insights into its role in disease pathology and may lead to the development of novel therapeutic strategies targeting RNA processing abnormalities.
Antibody Name:
ZC3H7B Antibody (PACO21976)
Antibody SKU:
PACO21976
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human ZC3H7B.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from 293 cells, using ZC3H7B antibody.
Background:
a tetratricopeptide (TPR) protein containing 5 zinc fingers. Interacts with the rotavirus non-structural protein NSP3. TPR proteins are involved in a variety of biological processes, such as cell cycle regulation, transcriptional control, mitochondrial and peroxisomal protein transport, neurogenesis and protein folding. Rush J., Nat. Biotechnol. 23:94-101(2005).
Synonyms:
KIAA1031; ROXN; Rotavirus X associated non-structural protein; Z3H7B; ZC3H7B
UniProt Protein Function:
RoXaN: a tetratricopeptide (TPR) protein containing 5 zinc fingers. Interacts with the rotavirus non-structural protein NSP3. TPR proteins are involved in a variety of biological processes, such as cell cycle regulation, transcriptional control, mitochondrial and peroxisomal protein transport, neurogenesis and protein folding.Protein type: RNA-binding; DNA-binding; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 22q13.2Cellular Component: nucleusMolecular Function: metal ion binding; protein bindingBiological Process: viral reproduction
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that contains a tetratricopeptide repeat domain. The encoded protein also interacts with the rotavirus non-structural protein NSP3. [provided by RefSeq, Jul 2008]
