Description
Anti-BOC Antibody (CAB7174)
The Brother of CDO Polyclonal Antibody (CAB7174) is a valuable tool for researchers studying the Brother of CDO (BOC) protein. Raised in rabbits, this antibody is highly specific to human samples and is validated for use in Western blot applications. It binds to the BOC protein, allowing for accurate detection and analysis in various cell types.BOC is known for its role in cell adhesion and signaling pathways, making it a key player in processes such as cell proliferation, differentiation, and migration.
By targeting BOC, researchers can gain insights into the mechanisms underlying these cellular functions, as well as its implications in diseases such as cancer and developmental disorders.Overall, the Brother of CDO Polyclonal Antibody (CAB7174) is a valuable tool for researchers looking to further understand the functions and implications of the BOC protein in various biological contexts.
| Antibody Name: | Anti-BOC Antibody |
| Antibody SKU: | CAB7174 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human BOC (NP_150279.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-431, SW480, U-251MG, SKOV3, HeLa, Mouse lung, Mouse brain, Rat spinal cord |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human BOC (NP_150279.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MLRG TMTA WRGM RPEV TLAC LLLA TAGC FADL NEVP QVTV QPAS TVQK PGGT VILG CVVE PPRM NVTW RLNG KELN GSDD ALGV LITH GTLV ITAL NNHT VGRY QCVA RMPA GAVA SVPA TVTL A |
| Gene ID: | 91653 |
| Uniprot: | Q9BWV1 |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
| Calculated MW: | 100kDa/121kDa |
| Observed MW: | 121kDa |
| Synonyms: | BOC, CDON2 |
| Background: | The protein encoded by this gene is a member of the immunoglobulin/fibronectin type III repeat family. It is a component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells, and promotes myogenic differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | BOC: Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion; Cell development/differentiation Chromosomal Location of Human Ortholog: 3q13.2 Cellular Component: cell soma; plasma membrane; integral to membrane Molecular Function:protein binding Biological Process: axon guidance; smoothened signaling pathway; muscle cell differentiation; positive regulation of muscle cell differentiation; cell adhesion; positive regulation of myoblast differentiation |
| NCBI Summary: | The protein encoded by this gene is a member of the immunoglobulin/fibronectin type III repeat family. It is a component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells, and promotes myogenic differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014] |
| UniProt Code: | Q9BWV1 |
| NCBI GenInfo Identifier: | 74761309 |
| NCBI Gene ID: | 91653 |
| NCBI Accession: | Q9BWV1.1 |
| UniProt Secondary Accession: | Q9BWV1,Q6UXJ5, Q8N2P7, Q8NF26, A6NJ30, B2RMS8, D3DN70 |
| UniProt Related Accession: | Q9BWV1 |
| Molecular Weight: | 1114 |
| NCBI Full Name: | Brother of CDO |
| NCBI Synonym Full Names: | BOC cell adhesion associated, oncogene regulated |
| NCBI Official Symbol: | BOCÂ Â |
| NCBI Official Synonym Symbols: | CDON2Â Â |
| NCBI Protein Information: | brother of CDO; Boc homolog; brother of CDON; cell adhesion associated, oncogene regulated 2 |
| UniProt Protein Name: | Brother of CDO |
| Protein Family: | Brother of CDO |
| UniProt Gene Name: | BOCÂ Â |
| UniProt Entry Name: | BOC_HUMAN |
 | Western blot analysis of extracts of various cell lines, using BOC antibody (CAB7174) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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