The Anti-Galectin-3 (LGALS3) Antibody (CAB14619) offered by Assay Genie is a valuable tool for researchers studying Galectin-3, a protein implicated in various cellular processes such as cell adhesion, proliferation, and apoptosis. This polyclonal antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the Galectin-3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in cancer research, immunology, and more.Galectin-3 is a multifunctional protein known for its involvement in tumor progression, immune response modulation, and inflammation regulation.
Its dysregulation has been linked to various diseases, making it a promising target for therapeutic interventions. By further investigating the role of Galectin-3 in these disease contexts, researchers can uncover valuable insights that may lead to the development of novel treatments and diagnostic tools. The Anti-Galectin-3 (LGALS3) Antibody provides researchers with a reliable tool to advance their understanding of Galectin-3 biology and its implications in disease mechanisms.
Product Name:
Galectin 3/LGALS3 Rabbit Polyclonal Antibody
SKU:
CAB14619
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 105-250 of human Galectin 3/LGALS3 (NP_002297.2).
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3958
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Galectin 3/LGALS3 Rabbit pAb (CAB14619) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
