10494 results for 'leptin receptor post'

The human body is a complex and intricate system where various components work together to maintain health and combat potential threats. Among these essential players are the TNF cy ...

Chemokines are highly conserved cytokines that control the movement of cells around the body. All 45 members of the chemokine family can be divided into 4 subfamilies depending on t ...

Histamine, a biogenic amine, plays a crucial role in various physiological processes, including immune responses, gastric acid secretion, and neurotransmission. Central to the action of histamine ...

Ionotropic glutamate receptors (iGluRs) are pivotal in the fast excitatory synaptic transmission in the mammalian central nervous system (CNS). These receptors are not only crucial for normal bra ...

What Are GPCRs? GPCRs, or G protein-coupled receptors, are a large family of membrane proteins that play a crucial role in cell signaling. They are involved in tran ...

Toll-Like Receptors The innate immune response has come under the spotlight in recent years due to its central role in propagating the pathoge ...

By Dr. Lisa Dwane, Postdoctoral Researcher, Royal College of Surgeons in Ireland The first link between estrogen and breast cancer was made in the ...

Glutamate receptors are pivotal in mediating excitatory neurotransmission in the central nervous system (CNS), playing crucial roles in synaptic transmission, plasticity, learning, and memory. Th ...

What are Toll Like Receptors? Toll-like receptors (TLRs) are a class of proteins that play a crucial role in the immune system's defense against microbial invaders ...

In the intricate landscape of the immune system, toll-like receptors (TLRs) play a fundamental role in the first line of defense against pathogens. These receptors, essential components of the in ...

Quick Facts About VolagidemabWhat is Volagidemab?Volagidemab is a glucagon-like peptide-1 (GLP-1) receptor antagonist designed to regulate glucose metabolism and energy homeostasis.How ...

Quick Facts About BrodalumabWhat is Brodalumab?Brodalumab is a monoclonal antibody that targets the IL-17 receptor to treat immune-mediated conditions like moderate-to-severe plaque pso ...

Quick Facts About ErenumabWhat is Erenumab?Erenumab is a fully human monoclonal antibody designed to prevent migraines by targeting the calcitonin gene-related peptide (CGRP) receptor.

The innate immune system, a primary line of defense against pathogens, comprises various cellular and molecular mechanisms. Among these, the Nod-like Receptor (NLR) signaling pathways play a crit ...

Imagine a world where cancer treatment is no longer a blunt instrument but a precision-guided surgical strike, executed by the body's own immune system. For years, we have dreamed of 'smart' cells t ...

Imagine an elite squad of soldiers sent to neutralize a hidden fortress, only to find themselves wandering aimlessly in a thick, disorienting fog just outside the gates. This is the current reality ...

We know it gets tiring being in the lab every day, especially with the evenings getting darker and gloomier. So, to get you in the festive spirit, we're holding a competition to win money to t ...

Science communication (Scicomm) is currently on the up. As rebellion against the increasing distrust of science stemmed from bigoted and ignorant leaders, scientists are turning to ...

Stress and anxiety are a normal part of our daily lives and impact everything we do from our relationships with loved ones to our performance in the laboratory. Like any scientist, I experienced ...

Social media has become a powerful tool for science communication, and Instagram is no exception. The platform is home to a diverse array of science influencers, ranging from PhD students to esta ...

I'll start this post off with a story. When I was half way through my PhD and I had found my passion for science communication, I approached my supervisor for the first time to ask “Can I h ...

Making the switch! This article provides some help on CV writing tips for scientists for PhDs and PostDocs looking for jobs outside of academia and what they might need to ...

The prevalence of obesity and its associated metabolic disorders has risen dramatically in recent decades, presenting a significant global health challenge. Adipose tissue, once considered mer ...

The lab can be one of the greatest places in the world to make live long friends. Spending countless hours in a tissue culture room late into the middle of the night, sharing similar frustrati ...

What do scientists consider their skill set when looking for jobs outside of academia? Mine where hard to sum. I was a PhD in cell biology. I could Western Blot, I had used thousands of ant ...

After probably a round or two of interviews and a PhD in your pocket you would think that proving yourself in your new lab would not be an issue. After all, they did hire you because you were ...

Over the past few years I have traversed through academia in a few different guises, first as a PhD student for about 5 years, then onto the traditional route of a post-doc, followed by a sale ...

PhD Interview Presentation Dos and Don’ts It is becoming increasingly common for master's and undergraduate students to present data they produced during their rese ...

It’s not uncommon now for Masters or Undergraduate students to present some data or data that they produced during their research for a PhD interview process. Sometimes this can be in front of ...

PhD Summit - A Virtual Conference ELISA Genie is proud to announce the launch of a groundbreaking virtual conference - PhD Sum ...

SciencePicture.Co— Scientific & Medical Illustration About SciencePicture.Co is a science and med ...

Revolutionizing Research with AI Abstract Generator Explore how GPT can help in generating scientific abstracts based on figure legends and data. Discover the potential of AI in scientifi ...

At ELISA Genie we are hugely interested in the future of science and we feel that PhD students are at the heart of this. Our new series, #LabChats, will see us interview different scient ...

Over the past few years momentum has gained in the scientific publishing community for researchers to publish their data in open access scientific journals. Open access to published research o ...

Writing a Thesis Statement Writing a thesis statement can be a frustrating task, whether you're working on your undergraduate, master's, or PhD degree. Unfortunatel ...

Objectives & Key Results Objectives & Key Results (OKRs) is a framework for setting and tracking goals. At Assay Genie, we've tailored this approach to sui ...

When PhDs and Post-Docs start in new lab they have the best intentions to keep their lab books up to date with notes, new research methods, data, and protocol information. These best efforts u ...

Like needles in a haystack, interesting speakers that bring charisma and rock n roll to their talks are hard to come by. No matter what the research interests of the audience, these speakers h ...

Explore 29 essential tips for crafting a compelling and well-structured PhD thesis, blending effective writing practices with time management and academic rigor for a successful dissertation jour ...

Introduction to Sci-Hub In the realm of science and academia, one name has been echoing in every corner of the globe, Sci-Hub. Created by Alexandra Elbakyan, a Kazakhstani computer scientis ...

Before I even started my PhD I was already thinking about carrying out PostDoc in a foreign country and had my sights set on going to the US. I had previously carried out a degree in Genetic ...

How to increase lab productivityWhen you look back at some weeks in the lab it seems like you have achieved nothing and your lab productivity can be low. Your cloning hasn’t worked or your mice ...

During my PhD I knew how networking was important, it helped me source reagents off other labs, get the best advice and helped me land a post doc at Cambridge University. Its not ...

Since I am from Ireland I thought I would give as comprehensive view as possible for Research Universities in Ireland. By now you are probably considering looking for a PhD or PostDoc posit ...

In the realm of biological and biochemical research, solutions play a pivotal role in various experimental procedures, from cell culture to molecular biology assays. Among the plethora ...

Delighted to be featured on Sophie Arthur’s blog, Soph Talks Science, where she interviews PhDs about their lives as researchers. Some great pieces on the site that are linkedin with the Instag ...

Writer’s block can be a big stumbling block when trying to write your PhD thesis, grant or a paper you are trying to get publish. During the early stages of writing my PhD thesis I s ...

Our Cancer Research Club symposium series continued on Wednesday afternoon, at Royal College of Surgeons (RCSI), Dublin, Ireland. The Bouchier-Hayes lecture theatre was at maximum capacity ...

Cell Signalling Cell signalling pathways have an important role in integrating a plethora of extracellular and intracellular signals to produce a controlled optimal ...

Explore the intricate world of Insulin Signaling and Receptor Tyrosine Kinases (RTKs), pivotal in regulating metabolism and influencing diseases like cancer and atherosclerosis. Key Take ...

What is the Coronavirus Spike Protein? COVID-19, the newest coronavirus to gain international attention, is caused by severe acute respirato ...

Inflammasomes are complex intracellular structures that play a pivotal role in the immune response by detecting pathogenic microorganisms and sterile stressors. Their activation is a critical ste ...

The Notch signaling pathway is a highly conserved cellular communication system that plays a crucial role in various biological processes, including embryonic development, tissue homeostasis, ...

HMGB1 Functional Overview High mobility group box 1 ( HMGB1), a member of the high-mobility group (HMG) family, was first identified in the thymus in 1973 a ...

Platelet activation plays a pivotal role in hemostasis, the process that stops bleeding and initiates wound healing. Central to this process is the activation of G protein-coupled receptors (GPCR ...

Interleukin signaling is involved in a number of biological processes, including cell growth and differentiation, inflammation and immunity. Interleukins are glycoproteins which act on hem ...

Introduction Tumorigenesis, the process by which normal cells transform into cancer cells, is a multifaceted and complex event influenced by various internal and external factors. Among th ...

CB6, also known as Etesevimab, is a monoclonal antibody that targets the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. It neutralizes the virus by preventing it from bin ...

Interleukin 12 in COVID-19 Prophylactics Interleukin 12 is a cytokine with wide-reaching effects in the innate and adaptive immune system. O ...

Vascular Endothelial Growth Factor A (VEGFA) is a pivotal signaling protein involved in both vasculogenesis and angiogenesis, processes essential for the formation of blood vessels during embryon ...

In the intricate landscape of cellular communication, lies a sophisticated ...

By Francisco Algaba Chueco In this post we discuss a topic that everyone will have heard of. Let’s talk about migraines, a disorder that hides a huge p ...

Delving into TNF alpha's critical role in inflammation and its therapeutic targeting. Key Takeaways: TNF alpha is a crucial cytokine in inflammation and apoptosis. Its structure facilita ...

The angiotensin pathway is a pivotal hormonal system that plays a crucial role in regulating blood pressure and maintaining fluid and electrolyte balance within the body. This complex biochemical ...

Chemokines are small signaling proteins that play a crucial role in the immune system by directing the movement of cells, orchestrating immune responses, and maintaining tissue homeostasis. Th ...

Quick Facts About BasiliximabWhat is Basiliximab?Basiliximab is a monoclonal antibody targeting the CD25 subunit of the IL-2 receptor, primarily used to prevent organ transplant rejecti ...

By Anusha Senevirante, Post-Doctoral researcher, Imperial College London With non-communicable diseases (or NCDs, which include heart disease, diabetes, c ...

window.SHOGUN_IMAGE_V2_ELEMENTS = window.SHOGUN_IMAGE_V2_ELEMENTS || new Array(); window.SHOGUN_IMAGE_V2_ELEMENTS.push({ uuid: 's-45124fd5-9a75-444d-b680-b8339e2a814d' }) Progr ...

What are Natural Killer Cells? Natural Killer (NK) cells are a vital subset of lymphocytes, belonging to the same family as B cells and T cells, collectively known a ...

Tocilizumab (Actemra®) in COVID-19 Treatment What is Tocilizumab? Tocilizumab, also called atlizumab, is an immunosuppres ...

Epidermal Growth Factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor epidermal growth factor receptor (EGFR) which triggers ligand-induced ...

What is Hepatocyte Growth Factor? Hepatocyte growth factor (HGF) is a cytokine that is mainly produced by the liver. HGF is a pleiotrophic cytokine that regulates cell growth, motili ...

Katherine Edwards, PhD Student, Queen’s University Belfast Cytokines play a vital role in immune responses enabling cross-talk between different cell types ...

What You Need to Know About LusvertikimabWhat is Lusvertikimab?Lusvertikimab is a monoclonal antibody designed to inhibit the IL-4 receptor, a key player in regulating immune responses, ...

Platelets, the tiny cellular fragments found in our blood, play a crucial role in maintaining our overall health and well-being. From their role in blood clotting to their involveme ...

What is VEGF? Vascular Endothelial Growth Factors (VEGFs) are a group of homodimeric polypeptides, and are master regulators of vascular development, maintenance and ...

The orchestration of angiogenesis, the process by which new blood vessels form from pre-existing ones, is a complex symphony regulated by various molecular players. At the forefront of this in ...

By Eoin Mac Réamoinn Toll-like receptors (TLRs) are renowned for their fundamental roles in innate sensing and initiating inflammatory responses. TLR ...

Notch signalling pathway review The Notch signalling pathway is a highly conserved intercellular signalling pathway that regulates various cellular processes. The Notch receptor is a t ...

Fibroblast growth factors (FGFs) are pivotal in regulating cellular processes, including proliferation, differentiation, and survival. The FGF signaling pathways play a critical role in embryonic ...

Natural killer (NK) cells are a crucial component of the innate immune system and play a significant role in eliminating tumor cells. Unlike T cells, NK cells can recognize and kill canc ...

Bone Morphogenetic Proteins (BMP) were first discovered in the 1960s by Dr.Marshall Urist, an orthopaedic surgeon at UCLA (Urist 1965). BMPs are classically associated with their roles in limb ...

CAR T-cell therapy CAR (Chimeric Antigen Receptor) T-cell Therapy is a type of cancer treatment. CAR T-cells are made in the laboratory and they have an artificially created receptor on th ...

What is a Plasma Membrane? The plasma membrane, also known as the cell membrane, is a vital component of all cells. It is a thin, semi-permeable barrier that separat ...

By Rachel Bleach, PhD Student, RCSI By the age of 79 years, 1 in 14 women will develop breast cancer (Global Burden of Disease Cancer 2017). Beatson reporte ...

CD16, also known as FcγRIII (Fc gamma receptor III), plays a crucial role in the immune system, serving as a receptor for the Fc region of immunoglobulin G (IgG). This receptor is a key player in ...

A wide variety of cell surface receptors activate Ras GTPase, including the tyrosine receptor linked to the epidermal growth factor receptor (EGFR) (Wells 1999). Upon receptor stimulation, son ...

Nod-like receptors Nod like receptors (NLRs) are a versatile family of relatively recently discovered intracellular receptors which have a b ...

Growth factors play a vital role in the complex web of biological processes, serving as key regulators in various essential events. They exert significant influence over cruc ...

Understanding Lag-3, Tim-3, and TIGIT: Key Players in T Cell RegulationThe immune system's ability to regulate T cell responses is crucial for maintaining homeostasis and combating diseases such as c ...

Exploring IL-18: A key cytokine in inflammation and disease. Key Takeaways: IL-18, a pro-inflammatory cytokine, plays a pivotal role in immune responses, particularly in inducing Type II ...

Introduction to CD155 in Cancer ImmunotherapyCD155, also known as Poliovirus Receptor (PVR), is a transmembrane protein that plays a pivotal role in tumor immune evasion. While CD155 is ...

Apoptosis Unveiled: Your Complete Guide to Intrinsic & Extrinsic PathwaysAt Assay Genie we have created a comprehensive guide outlining everything you need to know about apoptosis!K ...

IntroductionThe human kinome is estimated to contain 518 genes, in comparison to the estimated 180 genes that comprise the phosphatome (Arena et al., 2005). These kinase genes represent a signi ...

CD16, also known as FcγRIII (Fc gamma receptor III), plays a crucial role in the immune system, serving as a receptor for the Fc region of immunoglobulin G (IgG). This receptor is a key player in ...

Leukemia Inhibitory Factor (LIF) is a cytokine that plays a crucial role in various physiological processes within the human body. It has gained significant attention in the field o ...

Lab PostersScientific & Inspirational Posters for Your LabEnhance your lab environment with Assay Genie's exclusive collection of scientific and inspirational posters. Designed to motiva ...

Adipocytokines or adipokines are bioactive molecules that are produced by adipose tissue. They comprise cytokines, chemokines coagulation factors and factors involved ...

Transcription Factor Assays Detect Transcription Factors via indirect ELISA methods! Detect transcription factors or study transcription fact ...

Cell-Based ELISA Kits No More Western Blots! Over 1,600 Cell-Based ELISA kits to measure the relative levels of intracellular and phosphorylat ...