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10303 results for 'part alpha nk1.1'

    The Rise of Alpha-Emitting Radiopharmaceuticals: A New Era in Targeted Cancer Therapy(Post)

    Imagine a microscopic sniper, capable of delivering a lethal blow to a single cancer cell while leaving its healthy neighbors virtually untouched. This is the promise of targeted alpha therapy, a re ...

    ​TNF alpha & Inflammation(Post)

    Delving into TNF alpha's critical role in inflammation and its therapeutic targeting. Key Takeaways: TNF alpha is a crucial cytokine in inflammation and apoptosis. Its structure facilita ...

    Department of Oncology Retreat 2025(Post)

    Department of Oncology RetreatAssay Genie was honoured to sponsor and participate in the inaugural 2025 Department of Oncology Retreat, hosted by the University of Lausanne and Lausanne ...

    Comprehensive Guide to Mononuclear Cells(Post)

    Mononuclear cells, as the name suggests, refer to a group of white blood cells characterized by the presence of a single nucleus. Understanding the nature, function, and significanc ...

    Interferons(Post)

    Interferons (IFNs) are a group of signalling proteins that are produced and released from cells in response to viral infection and other stimuli such as normal and tumour cell survival and ...

    Dendritic Cells - Markers, Activation & Subtypes(Post)

    Exploring the multifaceted role of dendritic cells in immune function and disease. Key Takeaways DCs are professional antigen-presenting cells that capture, process, and pres ...

    Decoding Parkinson's Disease: Insights into a Complex Neurological Disorder(Post)

    Parkinson's disease (PD) is a progressive neurological disorder that primarily affects the motor system, leading to a wide array of symptoms ranging from tremors and stiffness to bradykinesia (sl ...

    Natural Killer Cells: A Guide(Post)

    What are Natural Killer Cells? Natural Killer (NK) cells are a vital subset of lymphocytes, belonging to the same family as B cells and T cells, collectively known a ...

    Christmas Lab Party Competition | Assay Genie(Post)

    We know it gets tiring being in the lab every day, especially with the evenings getting darker and gloomier. So, to get you in the festive spirit, we're holding a competition to win money to t ...

    Fenofibrate Usage for Diabetes Damage(Post)

    Fenofibrate, also known as FEN, is a drug that is used to lower cholesterol levels. It works by blocking the absorption of dietary cholesterol in the small intestine and therefore, re ...

    MAPK Signaling in Inflammatory Cytokines Pathways(Post)

    The Mitogen-Activated Protein Kinase (MAPK) pathway is a pivotal signaling cascade that plays a crucial role in mediating cellular responses to various external stimuli. This pathway is intricate ...

    CD11b: Macrophages and Microglia Marker(Post)

    The immune system plays a critical role in defending the body against pathogens and maintaining tissue homeostasis. Within the intricate network of immune cells, CD11b, also known as inte ...

    EGF Family (Post)

    Epidermal Growth Factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor epidermal growth factor receptor (EGFR) which triggers ligand-induced ...

    An Overview of the glycoprotein GM-CSF(Post)

    This article breaks down the glycoprotein Granulocyte-macrophage colony-stimulating factor (GM-CSF) detailing its structure, function and therapeutic uses. It also describes its role in im ...

    TNF cytokines and their Receptors(Post)

    The human body is a complex and intricate system where various components work together to maintain health and combat potential threats. Among these essential players are the TNF cy ...

    What are the stages of Parkinson's disease?(Post)

    What is Parkinson’s disease? Parkinson's disease can be seen as a neurodegenerative disease because it is associated with the loss of nerve ce ...

    Basiliximab: Mechanism, Clinical Applications, and Research Advancements(Post)

    Quick Facts About BasiliximabWhat is Basiliximab?Basiliximab is a monoclonal antibody targeting the CD25 subunit of the IL-2 receptor, primarily used to prevent organ transplant rejecti ...

    Streptococcus pneumoniae: Pathogenesis, Diagnosis, and Treatment(Post)

    Streptococcus pneumoniae, commonly known as pneumococcus, is a Gram-positive, encapsulated bacterium that is a leading cause of respiratory and invasive diseases worldwide. It is part of ...

    T Cell Types, Activation, Polarization & Function(Post)

    T Cell Types, Activation, Polarization & Function A comprehensive guide to T cells! window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); wi ...

    Complete T Helper Cell Guide: Th1, Th2, Th17 & Functions(Post)

    window.SHOGUN_IMAGE_V2_ELEMENTS = window.SHOGUN_IMAGE_V2_ELEMENTS || new Array(); window.SHOGUN_IMAGE_V2_ELEMENTS.push({ uuid: 's-19118a5d-7dea-4fc9-8267-6237960845ca' }) The T ...

    Gut Inflammation and Inflammatory Diseases (Post)

    What is Gut Inflammation? The gut, or gastrointestinal (GI) tract is a long tube that starts from the mouth and extends to the anus. It includes various organs suc ...

    Bersanlimab: Revolutionizing Cancer Research with Anti-CD47 Therapeutics(Post)

    What You Need to Know About BersanlimabWhat is Bersanlimab?Bersanlimab is a cutting-edge anti-CD47 monoclonal antibody designed to disrupt cancer cells' evasion of immune detection.What ...

    Fibroblast Markers(Post)

    Fibroblasts, essential components of connective tissues, play vital roles in maintaining tissue structure and function. Their remarkable ability to produce and organize the extracellular matrix ...

    CD25 Marker(Post)

    CD25, a key molecule in immune regulation, is integral to the function of activated lymphocytes and regulatory T cells. It's central in mediating immune responses, with implications in autoimmune ...

    T Helper Cells: Th1, Th2, Th17 Differences & Functions [2026](Post)

    Complete T Helper Cell Guide: Th1, Th2, Th17 & Functions - Your Ultimate Resource from Assay GenieIn this guide, we will explore the differences between TH1 and TH2 cells, their cruc ...

    Farletuzumab: Advancing Antibody-Drug Conjugate Research in Ovarian Cancer(Post)

    Quick Facts About FarletuzumabWhat is Farletuzumab?Farletuzumab is a humanized monoclonal antibody targeting folate receptor alpha (FRα), a protein overexpressed in ovarian and other ep ...

    Estrogen and Breast Cancer: a Nuclear (Receptor) War(Post)

    By Dr. Lisa Dwane, Postdoctoral Researcher, Royal College of Surgeons in Ireland The first link between estrogen and breast cancer was made in the ...

    p38 MAPK Signaling Review(Post)

    The p38 MAPK signaling pathway is an intracellular signaling pathway that plays a crucial role in cellular responses to various stressors and inflammatory stimuli. It is a part of the larger MAPK ...

    GPCRs (G Protein Coupled Receptors): A Guide(Post)

    What Are GPCRs? GPCRs, or G protein-coupled receptors, are a large family of membrane proteins that play a crucial role in cell signaling. They are involved in tran ...

    Types of Glial Cells(Post)

    Microglia Astrocytes Oligodendrocytes Glial ...

    CD25 and Tregs: Understanding the Role of Regulatory T Cells in Tumor Immunity(Post)

    Regulatory T cells (Tregs) play a crucial role in maintaining immune balance by suppressing excessive immune responses that could lead to tissue damage. However, in the context of cancer ...

    CD31: A Comprehensive Look at an Essential Biomarker(Post)

    What is CD31? CD31, also known as PECAM-1, was originally described as a cell surface antigen present on platelets and megakaryocytes. CD31 is ...

    Adhesion molecules in atherosclerosis – ICAM1(Post)

    Adhesion Molecules Direct cell-cell interactions are maintained and regulated by cell adhesion molecules. The expression of adhesion molecule ...

    Praluzatamab: Unveiling the Promise of CD47-Targeted Therapy in Cancer Research(Post)

    Quick Facts About PraluzatamabWhat is Praluzatamab?Praluzatamab is an experimental monoclonal antibody that targets CD47, a “don’t eat me” signal used by cancer cells to evade immune de ...

    Biomarkers & Inflammatory markers of atherosclerosis(Post)

    As atherosclerosis is a complex inflammatory disease, there are many influential biomarkers that contribute to the disease’s progression as well as biomarkers from atherosclerosis related d ...

    Interleukin 12 (IL-12) in COVID-19 Vaccines(Post)

    Interleukin 12 in COVID-19 Prophylactics Interleukin 12 is a cytokine with wide-reaching effects in the innate and adaptive immune system. O ...

    Hydroxychloroquine: Potential Treatment for COVID-19(Post)

    Hydroxychloroquine: Potential Treatment for COVID-19 What is Hydroxychloroquine? Hydroxychloroquine (HC ...

    Leukemia Inhibitory Factor (LIF)(Post)

    Leukemia Inhibitory Factor (LIF) is a cytokine that plays a crucial role in various physiological processes within the human body. It has gained significant attention in the field o ...

    Platelets : The Unassuming Heroes of Blood Circulation(Post)

    Platelets, the tiny cellular fragments found in our blood, play a crucial role in maintaining our overall health and well-being. From their role in blood clotting to their involveme ...

    Neuroimmunology: The Immune System of the CNS(Post)

    What is Neuroimmunology? Neuroimmunology is a multidisciplinary scientific field dedicated to investigating the intricate and bidirectional interactions between the ...

    The Rat Effectively Models Signature Cytokines of T Helper Cells(Post)

    Understanding the immune system's intricacies requires models that accurately reflect its complexity. The rat, as a model organism, plays a crucial role in immunological research, particularly i ...

    Macrophage, M1 & M2, Polarization and Function(Post)

    What is a Macrophage? Macrophages are indeed a type of phagocyte, responsible for engulfing and destroying foreign particles and cellular debris. They are larger cells with more cytoplasm a ...

    Etigilimab: Unveiling the Role of Anti-TIGIT in Cancer Research(Post)

    Key Facts About EtigilimabWhat is Etigilimab?Etigilimab is an anti-TIGIT monoclonal antibody being studied for its potential role in cancer immunotherapy.What role does Etigilimab play ...

    Liposomal nanosilver encapsulation for cytotoxic assays(Post)

    Nanosilver is the most commercialised nanoparticle routinely used for its antibacterial purposes in food preservation, cosmetic and health products such as medical devices and wound treatme ...

    The role of IL-18 in health and disease(Post)

    Exploring IL-18: A key cytokine in inflammation and disease. Key Takeaways: IL-18, a pro-inflammatory cytokine, plays a pivotal role in immune responses, particularly in inducing Type II ...

    Narnatumab: Unveiling the Role of Anti-CD47 in Cancer Research(Post)

    Quick Facts About NarnatumabWhat is Narnatumab?Narnatumab is a monoclonal antibody targeting CD47, a key immune checkpoint that helps cancer cells evade destruction by the immune system ...

    CD47: Overcoming Tumor Evasion Through Macrophage Activation(Post)

    One of the greatest challenges in cancer therapy is how tumors evade immune detection. Among the mechanisms cancer cells exploit, the CD47 pathway has emerged as a major player in helpin ...

    CD52 Expression(Post)

    What is CD52? Cluster Of Differentiation 52 (CD52) is a highly expressed membrane glycoprotein which is present on the surface of immune cel ...

    Tomaralimab: Unveiling the Role of Anti-CD47 in Cancer Research(Post)

    Quick Facts About TomaralimabWhat is Tomaralimab?Tomaralimab is an anti-CD47 monoclonal antibody designed to enhance immune system recognition of cancer cells by blocking the "don't eat ...

    Ruplizumab: Unveiling the Role of Anti-CD47 in Cancer Research(Post)

    Quick Facts About RuplizumabWhat is Ruplizumab?Ruplizumab is an investigational monoclonal antibody designed to target CD47, a protein that helps cancer cells evade immune detection.Wha ...

    Microglial Functions: Immune Response + Neuroinflammation(Post)

    Key Takeaways: Microglia are immune cells in the CNS, originating from myeloid precursor cells. They surveil the CNS, respond to changes, and maintain neural health. Microglia exist in dif ...

    Transformation Protocol – Sample Transformation Protocols(Post)

    Introduction Transformation of bacteria with plasmids is not only of note for bacterial studies but also can be used for gene expression studies in mammalian cells. Most plasmids are of bac ...

    Ivuxolimab: Redefining Cancer Immunotherapy and Research(Post)

    Quick Facts About IvuxolimabWhat is ivuxolimab?Ivuxolimab is a monoclonal antibody targeting CD47, a "don't eat me" signal that cancer cells exploit to evade immune destruction.How does ...

    Anti-CTLA-4 Immunotherapy(Post)

    CD Markers Cluster of Differentiation (CD) markers play an important role in the differentiation of B cells, T cells and NK (natural killer) c ...

    Adalimumab: Mechanism, Clinical Applications, and the Role of Biosimilars(Post)

    Quick Facts About AdalimumabWhat is Adalimumab?Adalimumab is a fully human monoclonal antibody designed to neutralize tumor necrosis factor-alpha (TNF-α), a key cytokine involved in inf ...

    Icatolimab: Revolutionizing the Fight Against Cancer via CD47 Targeting(Post)

    Quick Facts About IcatolimabWhat is Icatolimab?Icatolimab is a monoclonal antibody designed to target CD47, a protein that cancer cells use to evade immune detection.How does Icatolimab ...

    Lemzoparlimab: Targeting CD47 for Cancer Immunotherapy Advancements(Post)

    Quick Facts About LemzoparlimabWhat is Lemzoparlimab?Lemzoparlimab is a monoclonal antibody that targets CD47, a protein known for its role in helping tumors evade the immune system. By ...

    How Furin and ACE2 Interact with the Spike on SARS-CoV-2(Post)

    What is the Coronavirus Spike Protein? COVID-19, the newest coronavirus to gain international attention, is caused by severe acute respirato ...

    Bevacizumab: Mechanism, Clinical Applications, and Biosimilar Insights(Post)

    Quick Facts About BevacizumabWhat is Bevacizumab?Bevacizumab is a monoclonal antibody that targets vascular endothelial growth factor (VEGF), inhibiting angiogenesis (the formation of n ...

    microbiota & immune system signaling | Assay Genie(Post)

    You are only part human. In some ways, you are as much bacteria as you are mammal, and in some ways bacteria make up far more of you than your own familiar cells and genes! It is becoming ...

    Cytokine Storms: What happens when the immune system overreacts?(Post)

    Discover the critical role of cytokines as signaling molecules in immune responses, their functions, and the impact of their dysregulation, including cytokine storms. Key Takeaways: C ...

    SIRPα Inhibition: Clearing Tumors by Promoting Phagocytosis(Post)

    Cancer cells are adept at avoiding destruction by the immune system, often exploiting specific pathways to escape detection and elimination. One of these key mechanisms involves the SIRP ...

    Anti-PD-L1: Targeting Tumor Evasion with Immune Checkpoint Blockade(Post)

    IntroductionCancer cells have developed sophisticated mechanisms to evade the immune system, particularly through the inhibition of T-cell responses. One such mechanism involves the prog ...

    Talacotuzumab: Exploring CD123-Targeting Therapies in AML and MDS Research(Post)

    Key Facts About TalacotuzumabWhat is Talacotuzumab?Talacotuzumab is a monoclonal antibody designed to target CD123, a protein commonly found on the surface of certain blood cancer cells ...

    Cyclophosphamide Side Effects(Post)

    Ovarian cancer is a set of malignancies that start in the ovaries, as well as adjacent portions of the fallopian tubes and peritoneum. Women have two ovaries, one on each side of the ...

    Immunopeptidomics: Mapping the Hidden Landscape of the Cancer Immunome(Post)

    Imagine a high-stakes game of hide-and-seek where the seeker is your immune system and the hider is a master of disguise: cancer. For decades, we believed the 'wanted' posters for tumor cells were l ...

    Exhibition at the University of Oxford's BioEscalator(Post)

    Showcasing Innovation Assay Genie recently took part in an engaging event at Oxford’s BioEscalator, a leading innovation hub supporting scientific progress and entrepreneurship. Th ...

    T cell Immunophenotyping - A Guide(Post)

    Introduction T lymphocytes are type of white blood cell that plays a crucial role in the immune system. There are many different types of T cells, and it is important to be able to di ...

    Physiological and Pathological functions of IL-36(Post)

    By Charlotte O'Donnell PhD Similar to IL-33, IL-36R ligands are involved in maintaining intestinal homeostasis. Analogous to IL-33, d is local ...

    A Guide To Tau Proteins & Tauopathies(Post)

    Explore the essential role of Tau proteins in neuronal health and their impact in neurodegenerative diseases, unfolding the complexity behind their functions and dysfunctions. Key Takeaways: ...

    Adaptive immune system molecules(Page)

    Co-stimulatory and Co-inhibitory Molecules in Adaptive Immunity The adaptive immune system is in part regulated by a vast array of co-stim ...

    COVID-19 Cytokine Storm Multiplex Assays(Page)

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    In Vivo Functional Grade Antibodies(Page)

    Functional Grade In Vivo AntibodiesOur low endotoxin mAbs for translational and preclinical animal studies are more efficacious and cost effective than competitors!Explore In Vivo mAbsE ...

    Rat Multiplex ELISA Panels(Page)

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    ELISA Sampler Packs Based on thousands of citations and years of scientific endeavour, Assay Genie has developed ELISA Sampler Packs. An ELISA Sampler Pack is a ...

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    TCA/Krebs Cycle Assays At Assay Genie we've developed a range of TCA assays for researchers to analyse key steps in the Krebs/TCA/Citric Acid cycle pathway. Different Products ...

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    What is IHC? Immunohistochemistry (IHC) is a valuable tool used for the identification of specific antigens within embedded tissue prepara ...

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