The Anti-CD22 Biotinylated Recombinant Rabbit Monoclonal Antibody (HDAB0224) is a powerful tool for research involving the CD22 cell surface molecule. CD22 is a B-cell-specific transmembrane protein known to be involved in B-cell signaling and regulation, making it a key target in studies of B-cell function and dysfunction.This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in a variety of applications including immunohistochemistry, flow cytometry, and ELISA. Its biotinylated form allows for easy detection and analysis of CD22 in various cell types, providing researchers with a valuable tool for investigating the role of CD22 in diseases such as B-cell lymphomas and autoimmune disorders.
By targeting CD22, researchers can gain insight into the mechanisms driving B-cell activation and function, as well as explore potential therapeutic strategies for diseases involving dysregulated B-cell activity. The Anti-CD22 Biotinylated Recombinant Rabbit Monoclonal Antibody (HDAB0224) is a reliable and versatile tool for researchers studying B-cell biology and immunology.
SKU:
HDAB0224
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM14
Synonyms:
SIGLEC-2, SIGLEC2
Applications:
ELISA, Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
CD22 (CD22 Molecule) is a Protein Coding gene. Diseases associated with CD22 include Refractory Hematologic Cancer and Hairy Cell Leukemia. Among its related pathways are Downstream signaling events of B Cell Receptor (BCR) and Hematopoietic cell lineage. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is SIGLEC3.
