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DECR1 Monoclonal Antibody [PAT3B2AT] (CPAB0246)

SKU:
CPAB0246
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT3B2AT
Applications:
ELISA
FC
$179
Frequently bought together:

Description

system_update_alt Datasheet
Product Name:DECR1 Antibody
Product Sku:CPAB0246
Size:5μg
Host Species:Mouse
Immunogen:Anti-human DECR1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human DECR1 protein 35-335 amino acids purified from Ecoli.
Clone:PAT3B2AT.
Reactivity:Human
Applications:ELISA, Flow Cytometry
Purification Method:DECR1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:DECR1 is a mitochondrial protein which exists as a homotetramer and is a member of a family of short-chain dehydrogenases/reductases. DECR1 acts as an auxiliary enzyme of beta-oxidation andt partakes in the metabolism of unsaturated fatty enoyl-CoA esters. in particular, DECR1 uses NADP+ to catalyze the reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA that can subsequently be used as an intermediate in the Krebs cycle. Furthermore, DECR1 is believed to work as a tumor suppressor, possibly downregulating the expression of Neu and slowing the rate of tumorigenesis.
Synonyms:2,4-dienoyl-CoA reductase, mitochondrial, 2,4-dienoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase [NADPH], DECR1, DECR, NADPH, SDR18C1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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