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HBV AG-1 Monoclonal Antibody [NYRHepB-1] (CPAB0376)

SKU:
CPAB0376
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Virus
Host Species:
Mouse
Isotype:
IgG2b
Clone:
NYRHepB-1
Applications:
IP
WB
ELISA
IHC
€660
Frequently bought together:

Description

system_update_alt Datasheet
Product Name:HBV AG-1 antibody
Product Sku:CPAB0376
Size:500μg
Host Species:mouse
Immunogen:r.Hep B vaccine (BTG)
Clone:NYRHepB-1.
Reactivity:Viral
Applications:Immuneprecipitation, Western Blot, ELISA, Immunohistochemistry
Purification Method:Ion exchange column.
Isotype:IgG2b
Background:Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA.
Synonyms:
Storage Buffer:In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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