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IL 10 Monoclonal Antibody [MI10-L2] (CPAB0347)

SKU:
CPAB0347
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgM
Clone:
MI10-L2
€660
Frequently bought together:

Description

system_update_alt Datasheet
Product Name:IL 10 Antibody
Product Sku:CPAB0347
Size:2x200μg
Host Species:Rat
Immunogen:r.Murine IL-1
Clone:MI10-L2
Reactivity:Mouse
Applications:
Purification Method:Boric Acid precipitation/ S-Sepharose.
Isotype:IgM
Background:IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Synonyms:B-TCGF, CSIF, TGIF, IL-10, IL10A, MGC126450, MGC126451, Cytokine synthesis inhibitory factor.
Storage Buffer:In lyophilized form, for long periods, store at 4ºC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20ºC.

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