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NFATC1 Monoclonal Antibody [PAT1C3AT] (CPAB0566)

SKU:
CPAB0566
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT1C3AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet
Product Name:NFATC1 Antibody
Product Sku:CPAB0566
Size:5μg
Host Species:Mouse
Immunogen:Anti-human NFATC1 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NFATC1 amino acids 428-716 purified from Ecoli.
Clone:PAT1C3AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:NFATC1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2a
Background:NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least 2 components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play an essential role in inducible gene transcription during immune response. NFATC1 is an inducible nuclear component. NFATC1 functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of NFATC1 may regulate inducible expression of different cytokine genes.
Synonyms:Nuclear factor of activated T-cells cytoplasmic 1, NFAT transcription complex cytosolic component, NF-ATc1, NFATc1, NF-ATc, NFATc, NFAT2, MGC138448.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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