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PPM1G Monoclonal Antibody [Pk1G6AT] (CPAB0141)

SKU:
CPAB0141
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
Pk1G6AT
Applications:
WB
ELISA
IHC
€149
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Description

system_update_alt Datasheet
Product Name:PPM1G Antibody
Product Sku:CPAB0141
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PPM1G mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PPM1G amino acids 317-546 purified from Ecoli.
Clone:Pk1G6AT.
Reactivity:Human
Applications:Western Blot, ELISA, Immunohistochemistry
Purification Method:PPM1G antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:PPM1G is part of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PPM1G is accountable for the dephosphorylation of Pre-mRNA splicing factors, an important factor for the formation of functional spliceosome. PPM1G regulates cell cycle progression. PPM1G mediates histone dephosphorylation/exchange in response to DNA damage or checkpoint recovery in higher eukaryotes. The degradation of p21/WAF1 induced by PPM1G is mediated in a proteasome-dependent manner. Protein phosphatase 1G regulates assembly and function of the beta-catenin degradation complex.
Synonyms:Protein Phosphatase 1G, PP2CG, PPP2CG, MGC1675, MGC2870, PP2C GAMMA, EC 3.1.3.16, Protein phosphatase 2C isoform gamma, PP2C-gamma, Protein phosphatase magnesium-dependent 1 gamma, Protein phosphatase 1C, PPM1G, PPM1C.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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