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SGTA Monoclonal Antibody [PAT19E8AT] (CPAB0651)

SKU:
CPAB0651
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT19E8AT
Applications:
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet
Product Name:SGTA Antibody
Product Sku:CPAB0651
Size:5μg
Host Species:Mouse
Immunogen:Anti-human SGTA mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SGTA protein 1-313 amino acids purified from Ecoli.
Clone:PAT19E8AT.
Reactivity:Other bodies
Applications:ELISA, Flow Cytometry
Purification Method:SGTA antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:SGTA is a ubiquitously expressed protein that contains three TPR protein-protein interaction duplicates. SGTA takes part as a component of the androgen receptor (AR)-chaperone-cochaperone complex, functions as a cochaperone and participates in androgen signaling. SGTA binds directly to HSC70 and HSP70 and mediates their ATPase activity. SGTA gene encodes a protein that is able to interact with the chief nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate. In addition, SGTA interacts with Vpu and Gag from HIV-1, SARS-CoV accessory protein 7a, DNAJC5 and DNAJC5B. Since this transcript is expressed universally in several tissues, SGTA serves a housekeeping function. While being involved in apoptosis and androgen signaling, SGTA is a possible molecule for polycystic ovary syndrome, a disorder characterized by androgen excess, obesity and menstrual disturbances.
Synonyms:alphaSGT, hSGT, SGT, Vpu-binding protein, UBP, Small glutamine-rich tetratricopeptide repeat-containing protein alpha, Alpha-SGT, SGT1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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