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VEGF Monoclonal Antibody [NYRhVEGF] (CPAB0032)

SKU:
CPAB0032
Product type:
Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgM
Clone:
NYRhVEGF
Application:
IP
Application:
WB
Application:
ELISA
€460
Frequently bought together:

Description

Technical Manual

VEGF Monoclonal Antibody [NYRhVEGF] (CPAB0032)

Product Name:VEGF Antibody
Product Sku:CPAB0032
Size:500μg
Host Species:Mouse
Purification Method:Boric acid precipitation Protein concentration 1mg/ml in PBS (after reconstitution).
Isotype:IgM
Background:Vascular endothelial growth factoris an important signaling proteininvolved in both vasculogenesisand angiogenesis. As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/macrophagemigration, neurons, cancer cells, kidney epithelial cells ).VEGF mediates increased vascular permeability, induces angiogenesis, vasculogenesis and endothelial cell growth, promotes cell migration, and inhibits apoptosis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesisand cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy.
Immunogen:r.HumanVEGF
Synonyms:Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609.
Clone:NYRhVEGF.
Reactivity:Human
Applications:Immuneprecipitation, Western Blot, ELISA
Storage Buffer:In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.