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SST Recombinant Protein (RPPB1373)

SKU:
RPPB1373
Product Type:
Recombinant Protein
Uniprot:
P61278
Research Area:
Hormones
€273
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Description

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Product Name:SST Recombinant Protein
Product Code:RPPB1373
Size:10mg
Target:SST
Synonyms:Growth hormone release-inhibiting factor, SST, SMS, SMST, GHIH.
Source:Synthetic
Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:The protein was lyophilized with no additives.
Solubility:It is recommended to reconstitute the lyophilized Somatostatin in sterile 18M?-cm H2O not less than 100 �g/ml, which can then be further diluted to other aqueous solutions.
Stability:Lyophilized SST although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Somatostatin should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Purity:Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Amino Acid Sequence:Ala-Gly-Cys-Lys-Asn-Phe- Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH

Somatostatin (also known as growth hormone inhibiting hormone (GHIH) or somatotropin release-inhibiting hormone (SRIF) is a peptide hormone that regulates the endocrine systemand affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids, the other of 28 amino acids.

Somatostatin Synthetic is a single, non-glycosylated polypeptide chain containing 14 amino acids, having a molecular mass of 1637.9 Dalton and a Molecular formula of C76H104N18O19S2. The CAS# is 38916-34-6.

UniProt Protein Function:SST: Somatostatin inhibits the release of somatotropin. Belongs to the somatostatin family.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted; Hormone

Chromosomal Location of Human Ortholog: 3q28

Cellular Component: extracellular space; cell soma; extracellular region

Molecular Function:hormone activity

Biological Process: response to drug; induction of apoptosis by hormones; response to amino acid stimulus; regulation of cell migration; G-protein coupled receptor protein signaling pathway; negative regulation of cell proliferation; synaptic transmission; hyperosmotic response; cell surface receptor linked signal transduction; cell-cell signaling; response to heat; response to steroid hormone stimulus; digestion; response to nutrient

NCBI Summary:The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]
UniProt Code:P61278
NCBI GenInfo Identifier:4507243
NCBI Gene ID:6750
NCBI Accession:NP_001039.1
UniProt Related Accession:P61278
Molecular Weight:
NCBI Full Name:somatostatin preproprotein
NCBI Synonym Full Names:somatostatin
NCBI Official Symbol:SST��
NCBI Official Synonym Symbols:SMST��
NCBI Protein Information:somatostatin
UniProt Protein Name:Somatostatin
UniProt Synonym Protein Names:Growth hormone release-inhibiting factorCleaved into the following 2 chains:Somatostatin-28; Somatostatin-14
Protein Family:Sucrose synthase
UniProt Gene Name:SST��
UniProt Entry Name:SMS_HUMAN

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