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Anti-GPRASP1 Antibody (CAB16090)

SKU:
CAB16090
Product Type:
Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 6 Anti-GPRASP1 Antibody CAB16090
  • Cell Biology Antibodies 6 Anti-GPRASP1 Antibody CAB16090
€139 - €419
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Description

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Antibody Name:Anti-GPRASP1 Antibody
Antibody SKU:CAB16090
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human GPRASP1 (NP_055525.3).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Mouse, Rat
Positive Samples:Rat eye, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human GPRASP1 (NP_055525.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SSLF WSGD EVTA KFHP GNRV KDSN RSMH MANQ EANT MSRS QTNQ ELYI ASSS GSED ESVK TPWF WARD KTNT WSGP REDP NSRS RFRS KKEV YVES SSGS EHED HLES WFGA GKEA KFRS KMRA GKEA NNRA RHRA KREA CIDF MPGS IDVI KKES CFWP EENA NTFS RPMI KKEA RARA MTKE EAKT KARA RAKQ EARS EEEA LIGT WFWA TDES SMAD EASI ESSL QVED ESII GSWF WTEE EASM GTGA SSKS RPRT DGER IGDS LFGA REKT SMKT GAEA TSES ILAA DDEQ VIIG S
Gene ID:9737
Uniprot:Q5JY77
Cellular Location:Cytoplasm
Calculated MW:156kDa
Observed MW:157kDa
Synonyms:GPRASP1, GASP, GASP-1, GASP1
Background:This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified.
UniProt Protein Function:GPRASP1: May modulate lysosomal sorting and functional down- regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes. Belongs to the GPRASP family.
UniProt Protein Details:

Protein type:Vesicle

Chromosomal Location of Human Ortholog: Xq22.1

Cellular Component: cytoplasm

Molecular Function:protein binding

Biological Process: endosome to lysosome transport

NCBI Summary:This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010]
UniProt Code:Q5JY77
NCBI GenInfo Identifier:150378489
NCBI Gene ID:9737
NCBI Accession:NP_001092880.1
UniProt Secondary Accession:Q5JY77,O43168, Q96LA1,
UniProt Related Accession:Q5JY77
Molecular Weight:55-66 kDa
NCBI Full Name:G-protein coupled receptor-associated sorting protein 1
NCBI Synonym Full Names:G protein-coupled receptor associated sorting protein 1
NCBI Official Symbol:GPRASP1  
NCBI Official Synonym Symbols:GASP; GASP1; GASP-1  
NCBI Protein Information:G-protein coupled receptor-associated sorting protein 1
UniProt Protein Name:G-protein coupled receptor-associated sorting protein 1
UniProt Gene Name:GPRASP1  
UniProt Entry Name:GASP1_HUMAN
Anti-GPRASP1 Antibody (CAB16090)Western blot analysis of extracts of various cell lines, using GPRASP1 antibody (CAB16090) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-GPRASP1 Antibody (CAB16090)Immunofluorescence analysis of L929 cells using GPRASP1 antibody (CAB16090) at dilution of 1:100. Blue: DAPI for nuclear staining.

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