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IgM Monoclonal Antibody (CPAB0611)

SKU:
CPAB0611
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
€215
Frequently bought together:

Description

system_update_alt Datasheet
Product Name:IgM Antibody
Product Sku:CPAB0611
Size:100μg
Host Species:
Immunogen:
Clone:
Reactivity:Other bodies
Applications:
Purification Method:IgM antibody was purified from mouse ascitic fluids by Protein-A chromatography.
Isotype:
Background:Immunoglobulin M (IgM) is a basic antibody produced by B cells. IgM is the first antibody to emerge in response to initial exposure to an antigen. IgM antibodies are found in the blood and lymph fluid and are the third most widespread serum Ig. Immunoglobulin M (IgM), being the 3rd most widespread serum Ig and exists in two forms- mostly as a pentamer (970kDa) but also as a hexamer. The pentameric IgM has 10 binding sites since each monomer has two antigen binding sites. Due to distance constraints in the hexameric complex, the J chain is found in pentameric IgM but not in the hexameric form. IgM antibodies, which appear early in the course of an infection, typically reappear to a smaller extent after additional exposure. IgM, as opposed to IgG antibodies, do not pass across the human placenta. These properties of IgM make it suitable for the diagnosis of infectious diseases.
Synonyms:
Storage Buffer:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.

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