Anti-ITM2A Antibody (CAB10385)

SKU:
CAB10385
€99 - €249

Description

Technical Manual

Anti-ITM2A Antibody

Product Name:Anti-ITM2A Antibody
Product SKU:CAB10385
Size:20uL, 50 uL
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Background:

This gene encodes a type II membrane protein that belongs to the ITM2 family. Studies in mouse suggest that it may be involved in osteo- and chondrogenic differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-263 of human ITM2A (NP_004858.1).
Sequence:

MVKIAFNTPTAVQKEEARQDVEALLSRTVRTQILTGKELRVATQEKEGSSGRCMLTLLGLSFILAGLIVGGACIYKYFMPKSTIYRGEMCFFDSEDPANSLRGGEPNFLPVTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLDLLLGNCYLMPLNTSIVMPPKNLVELFGKLASGRYLPQTYVVREDLVAVEEIRDVSNLGIFIYQLCNNRKSFRLRRRDLLLGFNKRAIDKCWKIRHFPNEFIVETKICQE

Gene ID:9452
Swiss Prot:O43736
Synonyms:ITM2A; BRICD2A; E25A
Calculated MW:24kDa/29kDa
Observed MW:30kDa
Reactivity:Mouse, Rat
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting
Positive Samples:Mouse brain, Mouse lung, Rat brain
Cellular Location:Membrane, Single-pass type II membrane protein

Product Images

Anti-ITM2A Antibody (CAB10385)

Western blot analysis of extracts of various cell lines, using ITM2A antibody (CAB10385) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.

Uniprot Information

NCBI Summary:This gene encodes a type II membrane protein that belongs to the ITM2 family. Studies in mouse suggest that it may be involved in osteo- and chondrogenic differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
UniProt Code:O43736
NCBI GenInfo Identifier:6016399
NCBI Gene ID:9452
NCBI Accession:O43736.2
UniProt Secondary Accession:O43736,Q6IBC9, B2R7X5, B4E062,
UniProt Related Accession:O43736
Molecular Weight:24,994 Da
NCBI Full Name:Integral membrane protein 2A
NCBI Synonym Full Names:integral membrane protein 2A
NCBI Official Symbol:ITM2A
NCBI Official Synonym Symbols:E25A; BRICD2A
NCBI Protein Information:integral membrane protein 2A
UniProt Protein Name:Integral membrane protein 2A
UniProt Synonym Protein Names:Protein E25
Protein Family:Integral membrane protein
UniProt Gene Name:ITM2A
UniProt Entry Name:ITM2A_HUMAN
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Additional Information

Product type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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