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[KO Validated] TTC11/FIS1 Rabbit Monoclonal Antibody (CAB19666)

SKU:
CAB19666
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
  • KO Validated Antibodies 2 Anti-TTC11 Antibody KO Validated CAB19666
  • KO Validated Antibodies 2 Anti-TTC11 Antibody KO Validated CAB19666
  • KO Validated Antibodies 2 Anti-TTC11 Antibody KO Validated CAB19666
  • KO Validated Antibodies 2 Anti-TTC11 Antibody KO Validated CAB19666
  • KO Validated Antibodies 2 Anti-TTC11 Antibody KO Validated CAB19666
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] TTC11/FIS1 Rabbit Monoclonal Antibody
SKU:CAB19666
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-122 of human TTC11/FIS1 (NP_057152.2).
Sequence:MEAV LNEL VSVE DLLK FEKK FQSE KAAG SVSK STQF EYAW CLVR SKYN DDIR KGIV LLEE LLPK GSKE EQRD YVFY LAVG NYRL KEYE KALK YVRG LLQT EPQN NQAK ELER LIDK AMKK DG
Tested Applications:WB IHC-P IF/ICC IP ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:TTC11; CGI-135; S1
Positive Sample:HeLa,HepG2,Mouse heart,Rat spleen,Rat brain
Conjugate:Unconjugated
Cellular Localization:Mitochondrion outer membrane, Peroxisome membrane, Single-pass membrane protein.
Calculated MW:17kDa
Observed MW:15kDa

Enables identical protein binding activity. Involved in several processes, including calcium-mediated signaling using intracellular calcium source; cellular calcium ion homeostasis; and mitochondrion organization. Acts upstream of or within mitochondrion morphogenesis. Located in mitochondrion and peroxisome. Is integral component of mitochondrial outer membrane and integral component of peroxisomal membrane. Part of protein-containing complex. Biomarker of Alzheimer's disease.

Purification Method:Affinity purification
Gene ID:51024
Clone Number:ARC5010-03
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and TTC11/FIS1 knockout (KO) HeLa(KO) cells, using [KO Validated] TTC11/FIS1 Rabbit mAb (CAB19666) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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