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MARK1/MARK2/MARK3/MARK4 Antibody (PACO01041)

SKU:
PACO01041
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
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Description

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Antibody Name:MARK1/MARK2/MARK3/MARK4 Antibody
Antibody SKU:PACO01041
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:Human, Mouse, Rat
Immunogen:synthesized peptide derived from the Internal region of human MARK1/2/3/4.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:MARK1; KIAA1477; MARK; Serine/threonine-protein kinase MARK1; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c; MARK2; EMK1; Serine/threonine-protein kinase MARK2; ELKL motif kinase 1; EMK-1; MAP/microtubule affin
UniProt Protein Function:MARK1: a member of the CAMKL family of protein kinases. The MARK group of kinases is apparently involved in the control of cell polarity, microtubule stability and cancer. MARK1 forms a tight association with Tau in neurofibrillary tangles in Alzheimer disease tissue.
UniProt Protein Details:

Protein type:Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; Kinase, protein; EC 2.7.11.1; EC 2.7.11.26; CAMK group; CAMKL family; MARK subfamily

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: cytoplasm; cytoskeleton; microtubule cytoskeleton; plasma membrane

Molecular Function:ATP binding; magnesium ion binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; protein serine/threonine kinase activity; tau-protein kinase activity

Biological Process: cytoskeleton organization and biogenesis; neuron migration; protein amino acid phosphorylation; Wnt receptor signaling pathway

UniProt Code:Q9P0L2
NCBI GenInfo Identifier:124056494
NCBI Gene ID:4139
NCBI Accession:Q9P0L2.2
UniProt Secondary Accession:Q9P0L2,Q2HIY1, Q5VTF9, Q5VTG0, Q96SW9, Q9P251, D3DTB0 D3DTB1,
UniProt Related Accession:Q9P0L2
Molecular Weight:84,911 Da
NCBI Full Name:Serine/threonine-protein kinase MARK1
NCBI Synonym Full Names:microtubule affinity regulating kinase 1
NCBI Official Symbol:MARK1  
NCBI Official Synonym Symbols:MARK; Par1c; Par-1c  
NCBI Protein Information:serine/threonine-protein kinase MARK1
UniProt Protein Name:Serine/threonine-protein kinase MARK1
UniProt Synonym Protein Names:MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c
Protein Family:Serine/threonine-protein kinase
UniProt Gene Name:MARK1  
UniProt Entry Name:MARK1_HUMAN

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