Anti-S100A13 Antibody (PACO20381)

Antibody Name:	S100A13 Antibody (PACO20381)
Antibody SKU:	PACO20381
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:	Human
Immunogen:	Synthetic peptide of human S100A13

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO20381(S100A13 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20381(S100A13 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland.

Synonyms:

S100 calcium binding protein A13

UniProt Protein Function:	Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine.
NCBI Summary:	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:	Q99584
NCBI GenInfo Identifier:	66737368
NCBI Gene ID:	6284
NCBI Accession:	NP_001019381.1
UniProt Secondary Accession:	Q99584,Q52PI9, Q6FGF8,
UniProt Related Accession:	Q99584
Molecular Weight:	10
NCBI Full Name:	protein S100-A13
NCBI Synonym Full Names:	S100 calcium binding protein A13
NCBI Official Symbol:	S100A13
NCBI Protein Information:	protein S100-A13
UniProt Protein Name:	Protein S100-A13
UniProt Synonym Protein Names:	S100 calcium-binding protein A13
UniProt Gene Name:	S100A13

ELISA Kits

Human S100A13 / S100 Calcium Binding Protein A13 ELISA Kit

Human S100A13 (S100 Calcium Binding Protein A13) ELISA Kit (HUES02350)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)