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ABCC6 Rabbit Polyclonal Antibody (CAB8100)

SKU:
CAB8100
Product Type:
Antibody
Applications:
WB
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Signal Transduction
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ABCC6 Rabbit Polyclonal Antibody
SKU:CAB8100
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 830-940 of human ABCC6 (NP_001162.4).
Sequence:AIAE MGSY QELL QRKG ALVC LLDQ ARQP GDRG EGET EPGT STKD PRGT SAGR RPEL RRER SIKS VPEK DRTT SEAQ TEVP LDDP DRAG WPAG KDSI QYGR VKAT VHLA YLR
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:ARA; PXE; MLP1; MRP6; PXE1; URG7; ABC34; GACI2; MOATE; MOAT-E; EST349056; ABCC6
Positive Sample:mouse liver,rat liver
Conjugate:Unconjugated
Cellular Localization:Basolateral cell membrane, Endoplasmic reticulum membrane, Multi-pass membrane protein, Single-pass membrane protein.
Calculated MW:165kDa
Observed MW:164kDa

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.

Purification Method:Affinity purification
Gene ID:368
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using ABCC6 antibody (CAB8100) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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