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ADM Rabbit Polyclonal Antibody (CAB8659)

SKU:
CAB8659
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Neuroscience
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ADM Rabbit Polyclonal Antibody
SKU:CAB8659
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ADM (NP_001115.1).
Sequence:SSYP TGLA DVKA GPAQ TLIR PQDM KGAS RSPE DSSP DAAR IRVK RYRQ SMNN FQGL RSFG CRFG TCTV QKLA HQIY QFTD KDKD NVAP RSKI SPQG YGRR R
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:AM; PAMP; ADM
Positive Sample:Mouse kidney
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:20kDa
Observed MW:20kDa

The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration.

Purification Method:Affinity purification
Gene ID:133
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Mouse kidney, using ADM Rabbit pAb (CAB8659) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.

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