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Anti-DEFB121 Antibody (CAB1208)

SKU:
CAB1208
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 2 Anti-DEFB121 Antibody CAB1208
  • Cell Biology Antibodies 2 Anti-DEFB121 Antibody CAB1208
  • Cell Biology Antibodies 2 Anti-DEFB121 Antibody CAB1208
€139 - €419
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Description

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Antibody Name:Anti-DEFB121 Antibody
Antibody SKU:CAB1208
Antibody Size:20uL, 50uL, 100uL
Application:IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human DEFB121 (NP_001011878.1).
Application:IHC IF
Recommended Dilution:IHC 1:50 - 1:100 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human DEFB121 (NP_001011878.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MKLL LLLL TVTL LLAQ VTPV MKCW GKSG RCRT TCKE SEVY YILC KTEA KCCV DPKY VPVK PKLT DTNT SLES TSAV
Gene ID:245934
Uniprot:Q5J5C9
Cellular Location:Secreted
Calculated MW:8kDa
Observed MW:
Synonyms:DEFB121, DEFB21, ESC42RELC
Background:This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. Two transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:DEFB121: Has antibacterial activity (Potential). Belongs to the beta-defensin family.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 20q11.21

Cellular Component: cell surface; extracellular region

Biological Process: defense response to bacterium; innate immune response

NCBI Summary:This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
UniProt Code:Q5J5C9
NCBI GenInfo Identifier:61212937
NCBI Gene ID:245934
NCBI Accession:Q5J5C9.1
UniProt Related Accession:Q5J5C9
Molecular Weight:~ 8kDa
NCBI Full Name:Beta-defensin 121
NCBI Synonym Full Names:defensin beta 121
NCBI Official Symbol:DEFB121  
NCBI Official Synonym Symbols:DEFB21; ESC42RELC  
NCBI Protein Information:beta-defensin 121
UniProt Protein Name:Beta-defensin 121
UniProt Synonym Protein Names:Beta-defensin 21; DEFB-21; Defensin, beta 121
Protein Family:Beta-defensin
UniProt Gene Name:DEFB121  
UniProt Entry Name:DB121_HUMAN
Anti-DEFB121 Antibody (CAB1208)Immunohistochemistry of paraffin-embedded human prostate using DEFB121 antibody (CAB1208) at dilution of 1:100 (40x lens).
Anti-DEFB121 Antibody (CAB1208)Immunofluorescence analysis of rat testis cells using DEFB121 antibody (CAB1208) at dilution of 1:100. Blue: DAPI for nuclear staining.
Anti-DEFB121 Antibody (CAB1208)Immunofluorescence analysis of mouse testis cells using DEFB121 antibody (CAB1208) at dilution of 1:100. Blue: DAPI for nuclear staining.

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