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Anti-DEFB4A Antibody (CAB1643)

SKU:
CAB1643
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 7 Anti-DEFB4A Antibody CAB1643
  • Cell Biology Antibodies 7 Anti-DEFB4A Antibody CAB1643
  • Cell Biology Antibodies 7 Anti-DEFB4A Antibody CAB1643
€139 - €419
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Description

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Antibody Name:Anti-DEFB4A Antibody
Antibody SKU:CAB1643
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-64 of human DEFB4A (NP_004933.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-64 of human DEFB4A (NP_004933.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MRVL YLLF SFLF IFLM PLPG VFGG IGDP VTCL KSGA ICHP VFCP RRYK QIGT CGLP GTKC CKKP
Gene ID:1673
Uniprot:O15263
Cellular Location:Secreted
Calculated MW:7kDa
Observed MW:Refer to figures
Synonyms:DEFB4A, BD-2, DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1
Background:Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation.
UniProt Protein Function:defensin, beta 2: Has antibacterial activity (Potential). Belongs to the beta-defensin family. LAP/TAP subfamily.
UniProt Protein Details:

Protein type:Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: Golgi lumen; extracellular region

Biological Process: G-protein coupled receptor protein signaling pathway; defense response to bacterium; innate immune response; immune response; chemotaxis

NCBI Summary:Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Oct 2014]
UniProt Code:O15263
NCBI GenInfo Identifier:3023383
NCBI Gene ID:100289462
NCBI Accession:O15263.1
UniProt Secondary Accession:O15263,Q52LC0,
Molecular Weight:7,038 Da
NCBI Full Name:Beta-defensin 4A
NCBI Synonym Full Names:defensin, beta 4B
NCBI Official Symbol:DEFB4B  
NCBI Official Synonym Symbols:DEFB4P  
NCBI Protein Information:beta-defensin 4B; defensin, beta 4, pseudogene
UniProt Protein Name:Beta-defensin 4A
UniProt Synonym Protein Names:Beta-defensin 2; BD-2; hBD-2; Defensin, beta 2; Skin-antimicrobial peptide 1; SAP1
UniProt Gene Name:DEFB4A  
UniProt Entry Name:DFB4A_HUMAN
Anti-DEFB4A Antibody (CAB1643)Immunohistochemistry of paraffin-embedded rat lung using DEFB4A antibody (CAB1643) at dilution of 1:100 (40x lens).
Anti-DEFB4A Antibody (CAB1643)Immunohistochemistry of paraffin-embedded mouse lung using DEFB4A antibody (CAB1643) at dilution of 1:100 (40x lens).
Anti-DEFB4A Antibody (CAB1643)Immunofluorescence analysis of A431 cells using DEFB4A antibody (CAB1643) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

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