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CSGALNACT2 Antibody (PACO04700)

SKU:
PACO04700
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$323
Frequently bought together:

Description

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Antibody Name:CSGALNACT2 Antibody
Antibody SKU:PACO04700
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:IHC:1:100-1:300
Species Reactivity:Human, Mouse
Immunogen:synthesized peptide derived from the Internal region of human CsGalNAcT-2.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:CSGALNACT2; CHGN2; GALNACT2; Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Chondroitin beta-1; 4-N-acetylgalactosaminyltransferase 2; Beta4GalNAcT-2; GalNAcT-2
UniProt Protein Function:GALNACT2: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Belongs to the chondroitin N- acetylgalactosaminyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Glycan Metabolism - chondroitin sulfate biosynthesis; Transferase; Membrane protein, integral; EC 2.4.1.174

Chromosomal Location of Human Ortholog: 10q11.21

Cellular Component: Golgi membrane; membrane; integral to Golgi membrane

Molecular Function:acetylgalactosaminyltransferase activity; metal ion binding; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity

Biological Process: chondroitin sulfate metabolic process; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; proteoglycan biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process; carbohydrate metabolic process; pathogenesis; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process

NCBI Summary:This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. The encoded protein is involved in elongation during chondroitin sulfate synthesis. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Dec 2012]
UniProt Code:Q8N6G5
NCBI GenInfo Identifier:60391915
NCBI Gene ID:55454
NCBI Accession:Q8N6G5.1
UniProt Secondary Accession:Q8N6G5,Q6MZJ5, Q6MZP6, Q8TCH4, Q9P1I6, B3KWL7,
UniProt Related Accession:Q8N6G5
Molecular Weight:38,440 Da
NCBI Full Name:Chondroitin sulfate N-acetylgalactosaminyltransferase 2
NCBI Synonym Full Names:chondroitin sulfate N-acetylgalactosaminyltransferase 2
NCBI Official Symbol:CSGALNACT2  
NCBI Official Synonym Symbols:CHGN2; PRO0082; GALNACT2; GALNACT-2  
NCBI Protein Information:chondroitin sulfate N-acetylgalactosaminyltransferase 2; beta 4 GalNAcT-2; chondroitin beta1,4 N-acetylgalactosaminyltransferase 2
UniProt Protein Name:Chondroitin sulfate N-acetylgalactosaminyltransferase 2
UniProt Synonym Protein Names:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2; Beta4GalNAcT-2; GalNAcT-2
Protein Family:Chondroitin sulfate N-acetylgalactosaminyltransferase
UniProt Gene Name:CSGALNACT2  
UniProt Entry Name:CGAT2_HUMAN

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