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Anti-HMG20A Antibody (CAB7286)

SKU:
CAB7286
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-HMG20A Antibody CAB7286
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-HMG20A Antibody CAB7286
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-HMG20A Antibody CAB7286
€139 - €419
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Description

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Antibody Name:Anti-HMG20A Antibody
Antibody SKU:CAB7286
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-347 of human HMG20A (NP_060670.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Reactivity:Human, Mouse
Positive Samples:Jurkat, 22Rv1, Mouse heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-347 of human HMG20A (NP_060670.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MENL MTSS TLPP LFAD EDGS KESN DLAT TGLN HPEV PYSS GATS STNN PEFV EDLS QGQL LQSE SSNA AEGN EQRH EDEQ RSKR GGWS KGRK RKKP LRDS NAPK SPLT GYVR FMNE RREQ LRAK RPEV PFPE ITRM LGNE WSKL PPEE KQRY LDEA DRDK ERYM KELE QYQK TEAY KVFS RKTQ DRQK GKSH RQDA ARQA THDH EKET EVKE RSVF DIPI FTEE FLNH SKAR EAEL RQLR KSNM EFEE RNAA LQKH VESM RTAV EKLE VDVI QERS RNTV LQQH LETL RQVL TSSF ASMP LPGS GETP TVDT IDSY MNRL HSII LANP QDNE NFIA TVRE VVNR LDR
Gene ID:10363
Uniprot:Q9NP66
Cellular Location:Nucleus
Calculated MW:8kDa/40kDa
Observed MW:41kDa
Synonyms:HMG20A, HMGX1, HMGXB1
Background:
UniProt Protein Function:HMG20A: Plays a role in neuronal differentiation as chromatin- associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 15q24

Cellular Component: nucleus

Molecular Function:protein binding; DNA binding; protein heterodimerization activity; chromatin binding; transcription factor activity

Biological Process: chromatin remodeling; establishment and/or maintenance of chromatin architecture; negative regulation of neuron differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter

UniProt Code:Q9NP66
NCBI GenInfo Identifier:74734297
NCBI Gene ID:10363
NCBI Accession:Q9NP66.1
UniProt Secondary Accession:Q9NP66,Q53G31, Q9NSF6, A6NHY3, D3DW78,
UniProt Related Accession:Q9NP66
Molecular Weight:347
NCBI Full Name:High mobility group protein 20A
NCBI Synonym Full Names:high mobility group 20A
NCBI Official Symbol:HMG20A  
NCBI Official Synonym Symbols:HMGX1; HMGXB1  
NCBI Protein Information:high mobility group protein 20A; high-mobility group 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1
UniProt Protein Name:High mobility group protein 20A
UniProt Synonym Protein Names:HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1
Protein Family:High mobility group protein
UniProt Gene Name:HMG20A  
UniProt Entry Name:HM20A_HUMAN
Anti-HMG20A Antibody (CAB7286)Western blot analysis of extracts of various cell lines, using HMG20A antibody (CAB7286) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-HMG20A Antibody (CAB7286)Immunohistochemistry of paraffin-embedded mouse brain using HMG20A antibody (CAB7286) at dilution of 1:100 (40x lens).
Anti-HMG20A Antibody (CAB7286)Immunofluorescence analysis of A-549 cells using HMG20A antibody (CAB7286).

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