Human EIF2AK3 Recombinant Protein (hFc Tag) (HDPT0494)

SKU:
HDPT0494
Product Type:
Recombinant Protein
Host Species:
HEK293
Reactivity:
Human
€550

Description

Human EIF2AK3 Recombinant Protein (hFc Tag)

Description:The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]
Product name:Human EIF2AK3 Recombinant Protein (hFc Tag)
Synonyms:PEK; PERK; WRS
Type:protein
Size:50 µg
Name:EIF2AK3
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:Contact Technical Support
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:EIF2AK3(Thr536-Asn1116)+hFc(Glu99-Ala330)
Gene ID:9451
Uniprot:Q9NZJ5
Molecular Weight:89.43 kDa
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