null

Anti-IL-6 Antibody (CAB2447)

SKU:
CAB2447
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:IL6 Rabbit Polyclonal Antibody
Antibody SKU:CAB2447
Antibody Size:50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide of human IL6
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:NCI-H460, 293T, K-562, Rat lung, Rat kidney
Immunogen:A synthetic peptide of human IL6
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:3569
Uniprot:P05231
Cellular Location:Secreted
Calculated MW:23kDa
Observed MW:26kDa
Synonyms:IL6, BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2, IFNB2, IL-6
Background:This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
UniProt Code:P05231
NCBI GenInfo Identifier:124347
NCBI Gene ID:3569
NCBI Accession:P05231.1
UniProt Secondary Accession:P05231,Q9UCU2, Q9UCU3, Q9UCU4,
UniProt Related Accession:P05231
Molecular Weight:212
NCBI Full Name:Interleukin-6
NCBI Synonym Full Names:interleukin 6
NCBI Official Symbol:IL6  
NCBI Official Synonym Symbols:HGF; HSF; BSF2; IL-6; IFNB2  
NCBI Protein Information:interleukin-6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; interferon, beta 2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor
UniProt Protein Name:Interleukin-6
UniProt Synonym Protein Names:B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2
Protein Family:Interleukin
UniProt Gene Name:IL6  
UniProt Entry Name:IL6_HUMAN
Anti-IL-6 Antibody (CAB2447)Western blot analysis of extracts of various cell lines, using IL6 antibody (CAB2447) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.

Related Products