Anti-MUC7 Antibody (PACO20977)

Antibody Name:	MUC7 Antibody (PACO20977)
Antibody SKU:	PACO20977
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:2000-1:5000, IHC:1:20-1:100
Species Reactivity:	Human
Immunogen:	Synthetic peptide of human MUC7

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20977(MUC7 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20977(MUC7 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acid, . This antimicrobial protein has antibacterial and antifungal activity. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.

Synonyms:

mucin 7, secreted

UniProt Protein Function:	Function: May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili.2 PublicationsManual assertion based on experiment in:Ref.5
NCBI Summary:	This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acids. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.[provided by RefSeq, Feb 2009]
UniProt Code:	Q8TAX7
NCBI GenInfo Identifier:	222418647
NCBI Gene ID:	4589
NCBI Accession:	NP_001138478.1
UniProt Secondary Accession:	Q8TAX7,Q9UCD7, Q9UCD8,
UniProt Related Accession:	Q8TAX7
Molecular Weight:	39,159 Da
NCBI Full Name:	mucin-7
NCBI Synonym Full Names:	mucin 7, secreted
NCBI Official Symbol:	MUC7
NCBI Official Synonym Symbols:	MG2
NCBI Protein Information:	mucin-7; MUC-7; apo-MG2; salivary mucin-7; mucin 7, salivary
UniProt Protein Name:	Mucin-7
UniProt Synonym Protein Names:	Apo-MG2; Salivary mucin-7
Protein Family:	Mucin
UniProt Gene Name:	MUC7
UniProt Entry Name:	MUC7_HUMAN

ELISA Kits

Human MUC7 / Mucin-7 ELISA Kit

Human MUC7 (Mucin 7) CLIA Kit (HUES01189)

Human Mucin-7 (MUC7) ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)