Anti-OR2S2 Antibody (CAB16136)

Antibody Name:	Anti-OR2S2 Antibody
Antibody SKU:	CAB16136
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human OR2S2 (NP_063950.2).

Application:	WB IHC
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	U-87MG, HepG2

Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human OR2S2 (NP_063950.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MEVT NVIF LGVP VLFI SFSY VFII TTIL RIPS AEGR KKVF STCS AHLT VVIV FYGT LFFM YGKP KSKD SMGA DKED LSDK LIPL FYGV VTPM LNPI IYSL R
Gene ID:	56656
Uniprot:	Q9NQN1
Cellular Location:	Cell membrane, Multi-pass membrane protein
Calculated MW:	35kDa
Observed MW:	35kDa

Synonyms:

OR2S2, OR37A, OST715

Background:

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional.

NCBI Summary:	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015]
UniProt Code:	Q9NQN1
NCBI GenInfo Identifier:	167830488
NCBI Gene ID:	56656
NCBI Accession:	NP_063950.2
UniProt Related Accession:	Q9NQN1
Molecular Weight:	Calculated: 35kDaObserved: 35kDa
NCBI Full Name:	olfactory receptor 2S2
NCBI Synonym Full Names:	olfactory receptor family 2 subfamily S member 2 (gene/pseudogene)
NCBI Official Symbol:	OR2S2
NCBI Official Synonym Symbols:	OR37A; OST715
NCBI Protein Information:	olfactory receptor 2S2
UniProt Protein Name:	Olfactory receptor 2S2
UniProt Synonym Protein Names:	Olfactory receptor OR9-3
Protein Family:	Olfactory receptor
UniProt Gene Name:	OR2S2
UniProt Entry Name:	OR2S1_HUMAN

	Western blot analysis of extracts of various cell lines, using OR2S2 antibody (CAB16136) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
	Immunohistochemistry of paraffin-embedded Rat brain using OR2S2 Rabbit pAb (CAB16136) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded Mouse brain using OR2S2 Rabbit pAb (CAB16136) at dilution of 1:100 (40x lens).

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)