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PDX-1 Monoclonal Antibody (CPAB0733)

SKU:
CPAB0733
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Applications:
WB
IHC
€149
Frequently bought together:

Description

system_update_alt Datasheet
Product Name:PDX-1 antibody
Product Sku:CPAB0733
Size:10μl
Host Species:
Immunogen:Recombinant PDX1 E.Coli derived.
Clone:
Reactivity:Other Polyclonal bodies
Applications:Western Blot, Immunohistochemistry
Purification Method:
Isotype:
Background:PDX1 activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. IPF1 is particularly involved in glucose-dependent regulation of insulin gene transcription. Pancreas Duodenum Homeobox-1 binds preferentially the DNA motif 5'-[ct]taat[tg]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, it is required for maintaining the hormone-producing phenotype of the beta-cell.
Synonyms:IPF1, IUF1, IDX-1, MODY4, PDX1, STF-1, Insulin promoter factor 1, Pancreas Duodenum Homeobox-1.
Storage Buffer:

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