PLAU Rabbit Polyclonal Antibody (CAB2181)
- SKU:
- CAB2181
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Description
Product Name: | PLAU Rabbit Polyclonal Antibody |
SKU: | CAB2181 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-180 of human PLAU (NP_002649.1). |
Sequence: | GSNE LHQV PSNC DCLN GGTC VSNK YFSN IHWC NCPK KFGG QHCE IDKS KTCY EGNG HFYR GKAS TDTM GRPC LPWN SATV LQQT YHAH RSDA LQLG LGKH NYCR NPDN RRRP WCYV QVGL KPLV QECM VHDC ADGK KPSS PPEE LKFQ CGQK TLRP RFKI I |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ATF; QPD; UPA; URK; u-PA; BDPLT5; PLAU |
Positive Sample: | HT-1080,Mouse kidney,Mouse brain,Rat kidney,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 49kDa |
Observed MW: | 49kDa |
This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method: | Affinity purification |
Gene ID: | 5328 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |