SLC6A6 Antibody (PACO23485)
- SKU:
- PACO23485
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | SLC6A6 Antibody (PACO23485) |
| Antibody SKU: | PACO23485 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human SC6A6. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from COLO205 cells, using SC6A6 antibody. |
 | Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using SC6A6 antibody. |
| Background: | Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake. |
| Synonyms: | Sodium- and chloride-dependent taurine transporter; SLC6A6; |
| UniProt Protein Function: | TAUT: Required for the uptake of taurine. Transports both taurine and beta-alanine which requires sodium ions. Chloride ions are necessary for optimal uptake. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily. |
| UniProt Protein Details: | Protein type:Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: 3p25.1 Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane Molecular Function:neurotransmitter:sodium symporter activity; taurine:sodium symporter activity Biological Process: amino acid metabolic process; amino acid transport; ion transport; neurotransmitter transport; taurine transport; transmembrane transport; transport |
| NCBI Summary: | This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
| UniProt Code: | P31641 |
| NCBI GenInfo Identifier: | 1352535 |
| NCBI Gene ID: | 6533 |
| NCBI Accession: | P31641.2 |
| UniProt Secondary Accession: | P31641,Q9BRI2, Q9BXB0, B2RNU7, |
| UniProt Related Accession: | P31641,AAB25509 |
| Molecular Weight: | |
| NCBI Full Name: | Sodium- and chloride-dependent taurine transporter |
| NCBI Synonym Full Names: | solute carrier family 6 member 6 |
| NCBI Official Symbol: | SLC6A6 |
| NCBI Official Synonym Symbols: | TAUT |
| NCBI Protein Information: | sodium- and chloride-dependent taurine transporter |
| UniProt Protein Name: | Sodium- and chloride-dependent taurine transporter |
| UniProt Synonym Protein Names: | Solute carrier family 6 member 6 |
| Protein Family: | Sodium- and chloride-dependent taurine transporter |
| UniProt Gene Name: | SLC6A6 |
| UniProt Entry Name: | SC6A6_HUMAN |
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