Anti-SOX14 Antibody (CAB13674)

Antibody Name:	Anti-SOX14 Antibody
Antibody SKU:	CAB13674
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 91-240 of human SOX14 (NP_004180.1).

Application:	WB IHC IF
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 91-240 of human SOX14 (NP_004180.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	RYVF PLPY LGDT DPLK AAGL PVGA SDGL LSAP EKAR AFLP PASA PYSL LDPA QFSS SAIQ KMGE VPHT LATG ALPY ASTL GYQN GAFG SLSC PSQH THTH PSPT NPGY VVPC NCTA WSAS TLQP PVAY ILFP GMTK TGID PYSS AHAT AM
Gene ID:	8403
Uniprot:	O95416
Cellular Location:	Nucleus
Calculated MW:	26kDa
Observed MW:	Refer to Figures

Synonyms:

SOX14, SOX28

Background:

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene are suggested to be responsible for the limb defects associated with blepharophimosis, ptosis, epicanthus inversus syndrome (BPES) and Mobius syndrome.

UniProt Protein Function:	SOX14: Acts as a negative regulator of transcription.
UniProt Protein Details:	Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 3q22-q23 Molecular Function:protein heterodimerization activity; sequence-specific DNA binding; chromatin binding Biological Process: transcription from RNA polymerase II promoter; nervous system development; visual perception; entrainment of circadian clock; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent
NCBI Summary:	This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene are suggested to be responsible for the limb defects associated with blepharophimosis, ptosis, epicanthus inversus syndrome (BPES) and Mobius syndrome. [provided by RefSeq, Jul 2008]
UniProt Code:	O95416
NCBI GenInfo Identifier:	6831689
NCBI Gene ID:	8403
NCBI Accession:	O95416.1
UniProt Secondary Accession:	O95416,Q3KPH7, B2RAC0,
UniProt Related Accession:	O95416
Molecular Weight:	240
NCBI Full Name:	Transcription factor SOX-14
NCBI Synonym Full Names:	SRY (sex determining region Y)-box 14
NCBI Official Symbol:	SOX14
NCBI Official Synonym Symbols:	SOX28
NCBI Protein Information:	transcription factor SOX-14; SRY-box 14; HMG box transcription factor SOX-14
UniProt Protein Name:	Transcription factor SOX-14
UniProt Synonym Protein Names:	Protein SOX-28
Protein Family:	Transcription factor
UniProt Gene Name:	SOX14
UniProt Entry Name:	SOX14_HUMAN

	Immunohistochemistry of paraffin-embedded rat liver using SOX14 antibody (CAB13674) at dilution of 1:100 (40x lens).
	Immunofluorescence analysis of MCF-7 cells using SOX14 antibody (CAB13674).

Antibodies

Anti-SOX14 Antibody (CAB7217)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)