Anti-SYCP2 Antibody (CAB16098)

Antibody Name:	Anti-SYCP2 Antibody
Antibody SKU:	CAB16098
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1231-1530 of human SYCP2 (NP_055073.2).

Application:	WB IF
Recommended Dilution:	WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	293T, Mouse testis, Rat testis

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1231-1530 of human SYCP2 (NP_055073.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	EIES PHIN ENYI QSKR EESH LASS LSKS SEGR EKTW FDMP CDAT HVSG PTQH LSRK RIYI EDNL SNSN EVEM EEKG ERRA NLLP KKLC KIED ADHH IHKM SESV SSLS TNDF SIPW ETWQ NEFA GIEM TYET YERL NSEF KRRN NIRH KMLS YFTT QSWK TAQQ HLRT MNHQ SQDS RIKK LDKF QFII IEEL ENFE KDSQ SLKD LEKE FVDF WEKI FQKF SAYQ KSEQ QRLH LLKT SLAK SVFC NTDS EETV FTSE MCLM KEDM KVLQ DRLL KDML EEEL LNVR RELM SVFM SHER NANV
Gene ID:	10388
Uniprot:	Q9BX26
Cellular Location:	Chromosome, Nucleus
Calculated MW:	175kDa
Observed MW:	176kDa

Synonyms:	SYCP2, SCP-2, SCP2
Background:	The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex.

UniProt Protein Function:	SYCP2: Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements. Belongs to the SYCP2 family.
UniProt Protein Details:	Protein type:Unknown function Chromosomal Location of Human Ortholog: 20q13.33 Cellular Component: lateral element
NCBI Summary:	The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex. [provided by RefSeq, Jul 2008]
UniProt Code:	Q9BX26
NCBI GenInfo Identifier:	23822155
NCBI Gene ID:	10388
NCBI Accession:	Q9BX26.2
UniProt Secondary Accession:	Q9BX26,O75763, Q5JX11, Q9NTX8, Q9UG27, A2RUE5,
UniProt Related Accession:	Q9BX26
Molecular Weight:	175,639 Da
NCBI Full Name:	Synaptonemal complex protein 2
NCBI Synonym Full Names:	synaptonemal complex protein 2
NCBI Official Symbol:	SYCP2
NCBI Official Synonym Symbols:	SCP2; SCP-2
NCBI Protein Information:	synaptonemal complex protein 2
UniProt Protein Name:	Synaptonemal complex protein 2
UniProt Synonym Protein Names:	Synaptonemal complex lateral element protein; hsSCP2
Protein Family:	Synaptonemal complex protein
UniProt Gene Name:	SYCP2
UniProt Entry Name:	SYCP2_HUMAN

	Western blot analysis of extracts of various cell lines, using SYCP2 antibody (CAB16098) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
	Immunofluorescence analysis of C6 cells using SYCP2 antibody (CAB16098) at dilution of 1:100. Blue: DAPI for nuclear staining.

Antibodies

SYCP2 Antibody (PACO01833)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)