TNNI3 Paired Monoclonal Antibody (CPAB0658)
- SKU:
- CPAB0658
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
Frequently bought together:
Description
system_update_alt Datasheet
| Product Name: | TNNI3 Paired Antibody |
| Product Sku: | CPAB0658 |
| Size: | 100μg |
| Host Species: | |
| Immunogen: | |
| Clone: | |
| Reactivity: | Other bodies |
| Applications: |
| Purification Method: | Purified monoclonal IgG by protein A chromatography. |
| Isotype: | |
| Background: | Troponin I (TnI), troponin T (TnT) and troponin C (TnC) form the troponin complex of the thin filaments of striated muscle. TnI is acts as the inhibitory subunit by blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains 3 genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TNNI3 gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in the TNNI3 gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |
| Synonyms: | Troponin I cardiac muscle, Cardiac troponin I, TNNI3, TNNC1, CMH7, RCM1, cTnI, CMD2A, MGC116817. |
| Storage Buffer: |
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