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Anti-TRIM4 Antibody (CAB15922)

SKU:
CAB15922
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 2 Anti-TRIM4 Antibody CAB15922
  • Immunology Antibodies 2 Anti-TRIM4 Antibody CAB15922
  • Immunology Antibodies 2 Anti-TRIM4 Antibody CAB15922
€139 - €419
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Description

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Antibody Name:Anti-TRIM4 Antibody
Antibody SKU:CAB15922
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TRIM4 (NP_149082.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:A375
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TRIM4 (NP_149082.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEAE DIQE ELTC PICL DYFQ DPVS IECG HNFC RGCL HRNW APGG GPFP CPEC RHPS APAA LRPN WALA RLTE KTQR RRLG PVPP GLCG RHWE PLRL FCED DQRP VCLV CRES QEHQ THAM APID EAFE SYRE KLLK SQRN LVAK MKKV MHLQ DVEV KNAT QWKD KIKS QRMR ISTE FSKL HNFL VEEE DLFL QRLN KEEE ETKK KLNE NTLK LNQT IASL KKLI LEVG EKSQ APTL ELLQ NPKE VLTR SEIQ DVNY SLEA VKVK TVCQ IPLM KEML KRFQ
Gene ID:89122
Uniprot:Q9C037
Cellular Location:Cytoplasm
Calculated MW:34kDa/54kDa/57kDa
Observed MW:57kDa
Synonyms:TRIM4, RNF87
Background:The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternatively spliced transcript variants that encode different isoforms have been described.
UniProt Protein Function:E3 ubiquitin-protein ligase. Mediates 'Lys-63'-linked polyubiquitination of the innate immune receptor DDX58, this linkage doesn't lead to proteasomal degradation but seems to enhance IFN induction.
NCBI Summary:The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternatively spliced transcript variants that encode different isoforms have been described.[provided by RefSeq, Jul 2010]
UniProt Code:Q9C037
NCBI GenInfo Identifier:209572691
NCBI Gene ID:89122
NCBI Accession:Q9C037.2
UniProt Secondary Accession:Q9C037,Q75MK1, Q96F06, Q9C036, A4D298,
UniProt Related Accession:Q9C037
Molecular Weight:34,194 Da
NCBI Full Name:E3 ubiquitin-protein ligase TRIM4
NCBI Synonym Full Names:tripartite motif containing 4
NCBI Official Symbol:TRIM4  
NCBI Official Synonym Symbols:RNF87  
NCBI Protein Information:E3 ubiquitin-protein ligase TRIM4
UniProt Protein Name:E3 ubiquitin-protein ligase TRIM4
UniProt Synonym Protein Names:RING finger protein 87; Tripartite motif-containing protein 4
Protein Family:E3 ubiquitin-protein ligase
UniProt Gene Name:TRIM4  
UniProt Entry Name:TRIM4_HUMAN
Anti-TRIM4 Antibody (CAB15922)Western blot analysis of extracts of A375 cells, using TRIM4 antibody (CAB15922) at 1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min.
Anti-TRIM4 Antibody (CAB15922)Immunohistochemistry of paraffin-embedded Human placenta using TRIM4 Rabbit pAb (CAB15922) at dilution of 1:100 (40x lens).
Anti-TRIM4 Antibody (CAB15922)Immunofluorescence analysis of L929 cells using TRIM4 antibody (CAB15922) at dilution of 1:100. Blue: DAPI for nuclear staining.

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