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Mycobacterium Tuberculosis (TB) Antibodies, Proteins & ELISA Kits

Mycobacterium tuberculosis Antibodies, Proteins & ELISA Kits | Assay Genie
Infectious Disease · Mycobacterium tuberculosis

Mycobacterium tuberculosis antibodies, proteins & ELISA kits

Tuberculosis is caused by Mycobacterium tuberculosis, an acid-fast bacillus that primarily infects the lungs and can persist as latent infection for years before reactivating.

M. tuberculosisESAT-6 / CFP-10Airborne
M. tuberculosis
Acid-fast bacillus
ESAT-6 / CFP-10
Key antigens
Airborne
Droplet nuclei
Latent
~1/4 of people
Overview

What is Mycobacterium tuberculosis?

Tuberculosis is caused by Mycobacterium tuberculosis, an acid-fast bacillus that primarily infects the lungs and can persist as latent infection for years before reactivating.

It spreads through airborne droplet nuclei. Research tools centre on antigens such as ESAT-6, CFP-10 and Ag85, supporting antibody assays, interferon-gamma release research and vaccine work.

Transmission & symptoms

Mycobacterium tuberculosis is an acid-fast bacillus transmitted by airborne droplet nuclei. It primarily infects the lungs and can persist for years as latent infection before reactivating; disease features chronic cough, fever, night sweats and weight loss.

Diagnosis & serology

Immune-based testing centres on interferon-gamma release in response to the specific antigens ESAT-6 and CFP-10 (IGRAs), distinguishing infection from BCG vaccination. ELISA and antigen tools support host-response and biomarker research.

Research applications

Research tools cover TB-specific antigens (ESAT-6, CFP-10, Ag85), macrophage receptors and restriction factors (mannose receptor/CD206, SLC11A1/NRAMP1, TLR2) and the IFN-gamma/TNF/IL-12 axis central to protective immunity.

Products

Mycobacterium tuberculosis antibodies, proteins & ELISA kits

Validated, in-stock research tools for Mycobacterium tuberculosis — every link checked and live.

FAQs

Mycobacterium tuberculosis — frequently asked questions

How is TB infection detected immunologically?
Interferon-gamma release assays (IGRAs) measure T-cell responses to ESAT-6 and CFP-10, which are absent from BCG and most environmental mycobacteria.
What are ESAT-6 and CFP-10?
They are M. tuberculosis-specific secreted antigens used to detect infection and study protective T-cell responses.
Which cytokines matter most in TB immunity?
IFN-gamma, TNF-alpha and IL-12 are central to containing M. tuberculosis; their disruption (e.g. by anti-TNF therapy) raises reactivation risk.
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